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Design principles, manufacturing and evaluation techniques of custom dynamic ankle-foot orthoses: a review study


Ankle-Foot Orthoses (AFO) can be prescribed to allow drop-foot patients to restore a quasi-normal gait pattern. Standard off-the-shelf AFOs are cost-effective solutions to treat most patients with foot and ankle weakness, but these devices have several limitations, especially in terms of comfort. Therefore, custom AFOs are increasingly adopted to address drop-foot when standard solutions are not adequate. While the solid ones are the most common type of AFO, providing full stability and strong resistance to ankle plantarflexion, passive dynamic AFOs (PD-AFOs) represent the ideal solution for patients with less severe ankle weakness. PD-AFOs have a flexible calf shell, which can bend during the stance phase of walking and absorb energy that can be released to support the limb in the push-off phase. The aim of this review is to assess the state-of-the-art and identify the current limitations of PD-AFOs. An extensive literature review was performed in Google Scholar to identify all studies on custom PD-AFOs. Only those papers reporting on custom PD-AFOs were included in the review. Non peer-reviewed papers, abstract shorter than three pages, lecture notes and thesis dissertations were excluded from the analysis. Particular attention was given to the customization principles and the mechanical and functional tests. For each topic, the main results from all relevant papers are reported and summarized herein. There were 75 papers that corresponded to the search criteria. These were grouped according to the following macro-topics: 16 focusing on scanning technologies and geometry acquisition; 14 on customization criteria; 19 on production techniques; 16 on mechanical testing, and 33 on functional testing. According to the present review, design and production of custom PD-AFOs are becoming increasingly feasible due to advancements in 3D scanning techniques and additive manufacturing. In general, custom PD-AFOs were shown to provide better comfort and improved spatio-temporal parameters with respect to standard solutions. However, no customization principle to adapt PD-AFO stiffness to the patient’s degree of ankle impairment or mechanical/functional demand has thus far been proposed.

Peer Review reports


Drop-foot is a severely disabling syndrome affecting the lower limb, generally associated with damage to or malfunction of the central or peripheral nervous system, such as peroneal nerve injury, or brain and spinal cord disorders. The term derives from the inability to dorsiflex the foot due to insufficiency of the main ankle dorsiflexor muscles, such as the tibialis anterior. This deficit is particularly critical in the swing phase of walking, resulting in higher risk of stumbling and falling. About 23% of patients with symptomatic herniated disc (incidence about 1% of EU population) and 20% of those affected by stroke (incidence about 0.1% of EU population) have been reported to suffer from foot drop [1, 2].

An Ankle-Foot Orthosis (AFO) is usually prescribed to compensate for the functional limitations due to the drop-foot condition. AFOs are meant to restore quasi-normal gait patterns in drop-foot patients by resisting the ankle joint moments in the swing phase of walking, thus reducing the risk of falling. While standard off-the-shelf AFOs are rather inexpensive (50–100 EUR), they have several limitations: 1) they are sold in limited sizes (e.g. small, medium and large); 2) they do not always match the patient’s foot and leg geometry; 3) they have fixed mechanical properties that cannot address patient-specific impairments or functional demand; 4) they do not address other foot morphological alterations, such as severely pronated feet.

Frequently, standard AFOs require further manual customization to include an orthotic insole. As reported in a recent review [3], AFO stiffness represents a key factor influencing the gait pattern of drop-foot patients, but no guidelines for AFO design customization have been established. While AFO stiffness is fundamental to sustain the foot in the swing phase, this mechanical parameter can affect the physiological ankle dorsiflexion and plantarflexion in the stance phase of walking.

AFOs are largely classifiable in the two main groups of passive and active, which can be exploded in further subgroups as follows:

  • Passive AFOs

    Rigid or solid: characterized by stiff shells which prevent ankle movement in the three anatomical planes;

    Dynamic: flexible in the sagittal plane, allow for some dorsi/plantarflexion movement. Flexibility can be provided by a deformable shell (non-articulated: e.g. posterior leaf spring or ventral shell spring as in Fig. 1) or via a fixed-stiffness hinge joint (articulated: spring-hinged posterior or ventral shell as in Fig. 1).

  • Active AFOs: articulated and fitted with powered actuators. Flexion/extension movements at the ankle joint are actively assisted by the actuators.

Fig. 1
figure 1

The four main types of PD-AFOs. Where: (1) is the calf strap; (2) is the calf shell; (3) is the foot plate, and (4) is the ventral shell. H is the variable or fixed-stiffness hinge joint connecting the foot plate to the calf or to the ventral shell

This study is a literature review on the customization, production and testing of passive dynamic AFOs (PD-AFOs). Design, development and application of dynamic AFOs for patients with different degrees of drop-foot conditions are benefitting from the latest advancements in additive manufacturing. It is now possible to print an AFO shell in any shape and with a variety of materials using different 3D printing technologies. While traditional production techniques can also be used, additive manufacturing is fast becoming the new gold standard to produce custom orthotic devices with improved comfort and performance with respect to off-the-shelf solutions. While interest in this field is continuously growing [4], the process for the custom design, testing and evaluation of dynamic AFOs has not been established, and no standards have been published. Therefore, a large number of design principles, AFO materials and testing protocols have been reported. This critical review of the literature is aimed at collecting and reporting the major studies on custom PD-AFOs to date so as to highlight the major stepping stones in the development of a new generation of custom AFOs and to identify the major issues that still need to be overcome in this process.

Material and methods

An extensive literature review was conducted between May and November 2021 on the Google Scholar online database. The following keywords were used, either alone or in combination, to find relevant papers for the present review: dynamic; AFO; ankle foot orthosis; custom; patient-specific orthotic; mechanical testing; functional evaluation; gait analysis; drop-foot; customization; 3D printing; additive manufacturing; comfort; design and finite element analysis (FEA). For the purposes of this review study, we defined PD-AFOs as orthoses characterized by significant flexibility of a posterior (i.e. posterior leaf spring) or anterior (i.e. ventral shell) support or fitted with a dynamic hinge joint with pre-compressed spring elements to control motion in the sagittal-plane (Fig. 1). Papers were not included in the review for the following reasons: not focusing on custom solutions (i.e. standard off-the-shelf AFOs); not focusing on passive dynamic AFOs (i.e. rigid or, active AFOs) or type not clearly defined. It should be pointed out that some authors used the term “dynamic” while referring to active AFOs — those with actuators. These papers, along with abstracts shorter than three pages, lecture notes, thesis dissertations and papers not published on peer-reviewed journals were also excluded from the review. The papers complying with the inclusion criteria were analyzed and grouped in five different macro-topics: a) scanning technologies and geometry acquisition; b) customization criteria; c) production techniques; d) mechanical testing, and e) functional evaluation.


A total of 242 papers were found. 75 of these complied with the inclusion criteria and were included in the review. Some of these papers covered more than one macro-topic specified in Material and Methods. The number of papers covering each topic follows:

  1. a)

    16 papers addressed and collected patient geometry of the shank and foot;

  2. b)

    14 papers reported AFO customization criteria other than those based on foot and leg morphology;

  3. c)

    19 papers reported the production techniques;

  4. d)

    16 papers investigated characterization of mechanical properties;

  5. e)

    33 papers reported the functional evaluation of patients/subjects.

A summary of the main results from the literature review on each topic is summed up in the following subsections.

  1. a)

    Scanning technologies and geometry acquisition

Custom AFOs are traditionally modelled by hand by the orthotist via thermal molding on models of the patient’s foot and leg. Traditionally, the plaster model is obtained by filling the negative impression of the patient’s cast with liquid plaster. The custom AFO is then manufactured over the positive model. This process, however, is time-consuming and highly operator-dependent. Therefore, in the last 10 years, new technologies to obtain a 3D digital replica of the patient’s geometry have been used to create a solid model of the foot and leg: laser-based scanners [5,6,7,8,9,10] (6 out of 16 studies); structured-light scanners [11,12,13] (3/16); computer tomography [5, 14,15,16] (4/16); 3D coordinate digitizer to acquire landmark positions [17, 18] (2/16), and photogrammetry [19] (1/16). According to recent reviews [20, 21], 3D scanning, computer tomography and optical motion capture systems all represent valid and reliable alternatives to traditional casting methods to obtain a solid model of the patient’s foot and leg geometry.

  1. b)

    Customization criteria

According to the present review, PD-AFOs are usually customized on the patient’s lower limb morphology. Few studies used a commercial customizable PD-AFO — the modular Intrepid Dynamic Exoskeletal Orthosis (IDEO) — featuring a posterior strut, the stiffness of which can be customized to the patient’s ankle ROM, the type and level of activities, body mass and load carriage requirements [22,23,24,25]. A similar modular design featuring a variable stiffness rod in relation to the patient’s degree of impairment was proposed [26]. However, no indications are provided on the weight and the direction (towards stiffer or more compliant) of each parameter on the strut rigidity. AFO stiffness optimization based on the minimization of knee angle and energy cost of walking was reported for children with cerebral palsy [27, 28]. A combination of the following parameters has also been used as input data to set the stiffness of the custom AFOs: the patient’s prior experience; visual observations of patient’s gait; body weight; muscle strength; severity of ankle deformity [29,30,31,32,33]. Only one study customized the AFO stiffness according to the natural ankle pseudo-stiffness [34]. The majority of the studies optimized the stiffness of the calf shell. Only one study reported the effect of footplate stiffness on ankle joint power in gait [35].

  1. iii)

    Production techniques

Additive manufacturing is becoming widely used in orthopaedics, since it allows to obtain complex shaped devices made with a number of different materials [20]. The present review, in agreement with two recent studies [36, 37], has shown that most 3D-printed PD-AFOs are manufactured via Selective Laser Sintering (SLS) [5, 6, 8, 14, 15, 18, 25, 26, 38,39,40,41,42] and Fused Deposition Modeling (FDM) – also known as Fused Filament Fabrication (FFF) – [10, 15, 17, 43, 44]. SLS works with a high-power laser to sinter polymer powders, while FDM adds melted thermoplastic filaments in consecutive stratified layers to create the object. Stereolithography (SLA) [7, 11] and Multi Jet Fusion (MJF) [11] are less frequently used to produce custom AFOs. In SLA, a UV laser induces polymerization of a photopolymer to obtain the object; in MJF, a fusing agent is deposited on layers of heated powder where the particles are fused together.

  1. iv)

    Mechanical testing

This section is reporting only studies related to the experimental analysis of custom-made PD-AFOs. Whenever the AFO type was not clearly defined as “dynamic”, it was decided to include only the manuscripts which reported the force/deformation properties, providing evidence of a dynamic behavior of the orthosis. Three review studies were found which reported stiffness values for a variety of AFOs — custom and off-the-shelf — and the testing methods [3, 45, 46]. Most of these studies investigated the stiffness properties in plantar-dorsiflexion in the range 20 deg plantar- to 30 deg dorsiflexion. Only one study assessed the AFO’s mechanical properties outside the sagittal plane [47].

Most studies assessed the stiffness properties of the strut component, i.e. the long, flexible part of the calf shell [17, 41, 47,48,49,50,51]. Fewer studies investigated the mechanical properties of other components, such as the foot plate [50], or isolated parts of the AFO [52]. Displacements during AFO deflection were assessed in two studies [49, 53], while only one study performed a fatigue test [44]. A few papers [17, 49, 52] reported the mechanical testing of dynamic AFOs which were customized on a healthy subject’s leg or on other geometrical models of the lower limb and not for drop-foot patients were included in this review. In general, the AFO foot plate is fixed, and bending moments/forces or displacements are applied to the calf shell, simulating ankle dorsiflexion. The reported bending stiffness of the strut, in terms of resistance to dorsiflexion moment, ranged between 0.12 and 8.9 N*m/deg across these studies [15, 17, 33, 41, 48,49,50]. The energy absorbed/released by custom AFOs during gait has been seldom addressed in the literature [29, 54].

Custom PD-AFOs have also been tested in-silico via FEA [17, 42, 48, 52,53,54]. Boundary conditions were generally consistent with those used for the experimental mechanical tests, when present. In addition to stiffness [17, 42], FEA allowed to estimate the maximum Von Mises stresses [52, 55] and displacements [53] of the analyzed AFOs. Only one study assessed the maximum Von Mises stress against the material yielding [52], and reported the safety factor of each component in simulated jogging and downhill walking tasks.

  1. e)

    Functional evaluation

Table 1 sums up the outcome of the literature review in relation to the functional evaluation of custom dynamic AFOs. Thirty-three papers published from 1999 to 2021 were retrieved and found relevant to the topic. In terms of populations investigated, custom AFOs were used for post-stroke patients (n = 6) [11, 34, 57, 58, 62, 64], for generic drop-foot and muscles weakness (n = 13) [8, 24, 30,31,32,33, 39, 40, 44, 50, 51, 56, 59], for lower limb reconstruction (n = 4) [22, 23, 25, 60], for cerebral palsy (n = 4) [27, 28, 61, 66], for Charcot–Marie–Tooth (n = 1) [29], in children with hemiplegia (n = 2) [63, 65], and in normal/healthy subjects (n = 3) [7, 35, 43]. Posterior Leaf Spring (PLS) are the most common types of AFOs functionally evaluated and were compared to solid and hinged AFOs, and/or to shod/barefoot conditions. Carbon-fiber was found to be the most used material; plastic (nylon and polyamide) and thermoplastic (polypropylene and polyurethane) were also used due to their favorable manufacturing process and compatibility with current 3D printing technology. In terms of functional evaluation, gait analysis during walking at comfortable speed was by far the most common motor task investigated. Three studies reported on stair ascent/descent, and two studies reported on walking over an inclined ramp or treadmill. In one study, the AFOs were evaluated in a static balance test. Spatio-temporal parameters and lower limb joint kinematics and kinetics (mainly in the sagittal plane) were usually recorded and analyzed. Two studies also reported on surface EMG of the main lower limb muscles. Six studies reported on other qualitative scores such as comfort or ease of use (donning and removing). In terms of spatio-temporal parameters, while it is difficult to compare the functional outcome of PD-AFOs customized and produced for different populations with ankle weakness, 8 studies reported improved gait velocity and stride length in custom AFOs with respect to solid AFOs or shod/barefoot conditions. Due to the flexibility of the calf shell, custom PD-AFOs can absorb and release energy during walking. The two studies that assessed this parameter reported a reduction in the energy cost of walking while wearing the optimal stiffness AFOs with respect to other AFOs.

Table 1 Literature review with respect to the papers reporting on the functional evaluation of custom PD-AFOs. For each paper, when present, it is reported the AFO type(s), the customization criteria, the materials, the functional data/parameters, and the main outcome. Comfort assessment or other subjective scores are also reported


The present review is aimed at investigating the current literature on the state-of-the-art of custom PD-AFOs design, production and testing. Although thermal molding of AFOs on solid models of the patients’ legs is the most used production method worldwide, 3D scanning techniques and additive manufacturing are becoming increasingly used in the production process of custom PD-AFOs. The following sections address the critical analysis of the literature on the macro-topics used to classify the studies.

The use of modern 3D scanning technologies allows for fast and accurate digitization of the patient’s foot and leg. Data can be stored and shared in various 3D file formats (e.g. STL, OBJ, etc.) which can be easily edited with several commercial (e.g. SolidWorks, Blender) or proprietary software. Some file formats are fully compatible with 3D printers (e.g. STL), thus the timing from geometry acquisition to AFO production is significantly reduced. Moreover, the same 3D file can be used and revised later without the need for a new acquisition of the patient’s geometry — in cases of wearing out, breakage or changes in the mechanical requirements. The dematerialization of the foot and leg 3D acquisition allows to share the geometry with the production facility, which can be remotely located with respect to the patient’s location. According to the present review, laser-based and structured-light scanners are the most common technologies for geometry acquisition. While the cost of high-quality 3D scanners and the expertise required to process the 3D files is limiting the spread of this technology, the development of low-cost 3D scanning solutions [13, 21, 67] is allowing more orthotic centers and research groups to advance the current methodology for geometrical reproduction from the traditional casting techniques.

The majority of the AFOs were customized according to morphological parameters only, regardless of body weight and/or functional requirement. Some studies reported that the AFO’s stiffness was customized on the patient’s body mass, load carriage requirements and/or range of available pain-free motion; however, the customization process was not sufficiently explained [22,23,24,25, 29,30,31, 34]. The IDEO was one of the most used custom AFOs across all studies [22,23,24,25, 39, 40, 60]. Although the IDEO can be customized to each patient and modulated according to changes in strength and functional ability [68], the relationship between the patient’s clinical deficit and functional requirements and the AFO’s mechanical properties and design features has not been standardized and reported to date.

With respect to AFO production, the growing demand for customized solutions is paving the way for additive manufacturing in the healthcare industry. 3D printers allow production of orthotic devices with complex shapes and have been successfully used to manufacture AFOs using a variety of materials, mostly polymers and composites. The combination of different materials in the same orthotic device is also possible. SLS was the most used technology to produce custom AFOs, as this allows several items to be produced simultaneously and has a lower environmental impact than FDM [69]. Although SLA and FDM are the most cost-effective solutions, SLS guarantees the highest accuracy and the fastest printing time [70].

Custom AFO stiffness was evaluated via mechanical tests simulating ankle flexion in gait. The bending stiffness, in terms of resistance to dorsiflexion moment, was significantly variable across studies as a consequence of the chosen design, material and thickness of the calf shell. Although standard testing methods to assess AFO stiffness under realistic biomechanical conditions have been proposed [71,72,73], most research groups developed custom setups and loading/displacement parameters. This made it difficult to compare the mechanical properties of AFOs with respect to materials and designs. Despite the importance of foot plate flexibility with respect to forefoot biomechanics in late stance, its mechanical properties and their effects on lower limb kinematics have not been sufficiently investigated to date. FEA allows to identify critical regions in terms of stress and strain under physiological loading conditions and to redesign high-stress regions exceeding the material yielding. This is particularly critical for dynamic AFOs with complex shapes subjected to large deformations. In addition, FEA is useful to minimize production costs by assessing different design solutions and materials before manufacturing. In terms of functional evaluation, the present review has revealed generally positive outcomes of custom AFOs with respect to the no-AFO condition and off-the-shelf/solid AFOs. While spatio-temporal, lower limb kinematic and kinetic parameters were frequently reported, subjective scores — such as comfort, walking confidence and ease of donning — were seldom implemented. Custom solutions scored better than standard/solid AFOs for comfort and satisfaction [7, 44, 57, 62]. It should be highlighted that the custom solutions were assessed against either barefoot or shod conditions. These two control conditions are biomechanically different, as the shoe’s weight significantly increases the plantarflexion moment at the ankle in the swing phase. Walking is the motor task most reported in the functional evaluation of AFOs. Few studies reported on other tasks, such as stair ascending/descending and ramp climbing. There is a lack of information on the biomechanical interaction between AFO and foot/leg for other major activities of daily living.

The present review should be interpreted with respect to some limitations. Since this study was meant to be a comprehensive literature review of the state of the art on PD-AFOs and not a systematic review, a research question was not formulated to compare the main outcomes across studies. The literature review was conducted on the Google Scholar database only. In addition, several studies did not clarify the AFO type — i.e. static/dynamic, standard/custom — therefore their classification was rather difficult, and these were excluded from the review.


According to the present review, custom PD-AFOs are becoming increasingly feasible due to advancements in 3D scanning techniques and in additive manufacturing. In general, custom PD-AFOs provide better comfort and more physiological spatio-temporal parameters than standard off-the-shelf solutions. However, no clear customization principles to customize PD-AFO stiffness with respect to the patient-specific degree of impairment or mechanical and functional request have thus far been proposed and reported. Healthcare providers and clinicians should agree and inform on which clinical, morphological or functional parameters are critical to the PD-AFO customization process. Scoring systems to quantify the relevant parameters should also be formulated to obtain a global score which can be associated to the most appropriate AFO stiffness. A standard testing method to measure AFO stiffness is necessary to allow quantitative comparison between PD-AFO types and materials.

Availability of data and materials

Data sharing not applicable to this article as no datasets were generated or analysed during the current study.



Ankle-Foot Orthosis


Passive Dynamic Ankle Foot Orthosis


Finite Element Analysis


Selective-Laser Sintering


Fused Deposition Modeling


Stereo Lithography


Multi-Jet Fusion


Fused Filament Fabrication


Posterior Leaf Spring


Intrepid Dynamic Exoskeletal Orthosis


  1. Ma J, He Y, Wang A, Wang W, Xi Y, Yu J, Ye X. Risk factors analysis for foot drop associated with lumbar disc herniation: an analysis of 236 patients. World Neurosurg. 2018;110:e1017–24.

    Article  PubMed  Google Scholar 

  2. Burridge JH, Taylor PN, Hagan SA, Wood DE, Swain ID. The effects of common peroneal stimulation on the effort and speed of walking: a randomized controlled trial with chronic hemiplegic patients. Clin Rehabil. 1997;11(3):201–10.

    CAS  Article  PubMed  Google Scholar 

  3. Totah D, Menon M, Jones-Hershinow C, Barton K, Gates DH. The impact of ankle-foot orthosis stiffness on gait: a systematic literature review. Gait Posture. 2019;69:101–11.

    Article  PubMed  Google Scholar 

  4. Wixted CM, Peterson JR, Kadakia RJ, Adams SB. Three-dimensional printing in Orthopaedic surgery: current applications and future developments. J Am Acad Orthop Surg Glob Res Rev. 2021;5(4):00230–11.

    Article  PubMed  Google Scholar 

  5. Milusheva SM, Tosheva EY, Hieu LC, Kouzmanov LV, Zlatov N, Toshev YE. Personalised Ankle-Foot Orthoses Design based on Reverse Engineering, Intell. Prod. Mach. Syst. - 2nd I*PROMS Virtual Int. Conf. 3–14 July 2006, Elsevier; 2006. p. 253–7.

    Book  Google Scholar 

  6. Pallari JHP, Dalgarno KW, Munguia J, Muraru L, Peeraer L, Telfer S, et al. Design and additive fabrication of foot and ankle-foot orthoses, 21st Annu. Int. solid free. Fabr. Symp. - An Addit. Manuf. Conf. SFF, vol. 2010; 2010. p. 834–45.

    Google Scholar 

  7. Mavroidis C, Ranky RG, Sivak ML, Patritti BL, DiPisa J, Caddle A, et al. Patient specific ankle-foot orthoses using rapid prototyping. J Neuroeng Rehabil. 2011;8:1–11.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Creylman V, Muraru L, Pallari J, Vertommen H, Peeraer L. Gait assessment during the initial fitting of customized selective laser sintering ankle foot orthoses in subjects with drop foot. Prosthetics Orthot Int. 2013;37(2):132–8.

    Article  Google Scholar 

  9. Roberts A, Wales J, Smith H, Sampson CJ, Jones P, James M. A randomised controlled trial of laser scanning and casting for the construction of ankle-foot orthoses. Prosthetics Orthot Int. 2016;40(2):253–61.

    Article  Google Scholar 

  10. Shih A, Park DW, Yang YY, Chisena R, Wu D. Cloud-based design and additive manufacturing of custom orthoses. Procedia CIRP. 2017;63:156–60.

    Article  Google Scholar 

  11. Liu Z, Zhang P, Yan M, Xie Y, Huang G. Additive manufacturing of specific ankle-foot orthoses for persons after stroke: a preliminary study based on gait analysis data. Math Biosci Eng. 2019;16(6):8134–43.

    Article  PubMed  Google Scholar 

  12. Pandey R, Singh R. Experimental Analysis of Various Materials on Custom-Fit Ankle Foot Orthosis. J Phys Conf Ser. 2021;1950:12028.

    CAS  Article  Google Scholar 

  13. Dombroski CE, Balsdon MER, Froats A. The use of a low cost 3D scanning and printing tool in the manufacture of custom-made foot orthoses: a preliminary study. BMC Res Notes. 2014;7(1):1–4.

    Article  Google Scholar 

  14. Faustini MC, Neptune RR, Crawford RH, Stanhope SJ. Manufacture of passive dynamic ankle-foot orthoses using selective laser sintering. IEEE Trans Biomed Eng. 2008;55(2):784–90.

    Article  PubMed  Google Scholar 

  15. Walbran M, Turner K, McDaid AJ. Customized 3D printed ankle-foot orthosis with adaptable carbon fibre composite spring joint. Cogent Eng. 2016;3(1):1227022.

    Article  Google Scholar 

  16. Alam M, Choudhury IA, Bin MA, Hussain S. Computer aided design and fabrication of a custom articulated ankle foot orthosis. J Mech Med Biol. 2015;15(04):1550058.

    Article  Google Scholar 

  17. Schrank ES, Hitch L, Wallace K, Moore R, Stanhope SJ. Assessment of a virtual functional prototyping process for the rapid manufacture of passive-dynamic ankle-foot orthoses. J Biomech Eng. 2013;135(10):101011–7.

    Article  PubMed  Google Scholar 

  18. Schrank ES, Stanhope SJ. Dimensional accuracy of ankle-foot orthoses constructed by rapid customization and manufacturing framework. J Rehabil Res Dev. 2011;48(1):31–42.

    Article  PubMed  Google Scholar 

  19. Dal Maso A, Cosmi F. 3D-printed ankle-foot orthosis: a design method. Mater Today Proc. 2019;12:252–61.

    Article  Google Scholar 

  20. Barrios-Muriel J, Romero-Sánchez F, Alonso-Sánchez FJ, Salgado DR. Advances in orthotic and prosthetic manufacturing: a technology review. Materials (Basel). 2020;13(2):295.

    CAS  Article  Google Scholar 

  21. Farhan M, Wang JZ, Bray P, Burns J, Cheng TL. Comparison of 3D scanning versus traditional methods of capturing foot and ankle morphology for the fabrication of orthoses: a systematic review. J Foot Ankle Res. 2021;14(1):1–11.

    Article  Google Scholar 

  22. Esposito ER, Ruble MD, Ikeda AJ, Wilken JM. The effect of custom carbon ankle-foot orthosis alignment on roll-over shape and center of pressure velocity. 2020.

    Book  Google Scholar 

  23. Russell Esposito E, Stinner DJ, Fergason JR, Wilken JM. Gait biomechanics following lower extremity trauma: amputation vs. reconstruction. Gait Posture. 2017;54:167–73.

    Article  PubMed  Google Scholar 

  24. Russell Esposito E, Blanck RV, Harper NG, Hsu JR, Wilken JM. How does ankle-foot orthosis stiffness affect gait in patients with lower limb salvage? Clin Orthop Relat Res. 2014;472(10):3026–35.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Haight DJ, Russell Esposito E, Wilken JM. Biomechanics of uphill walking using custom ankle-foot orthoses of three different stiffnesses. Gait Posture. 2015;41(3):750–6.

    Article  PubMed  Google Scholar 

  26. Deckers JP, Vermandel M, Geldhof J, Vasiliauskaite E, Forward M, Plasschaert F. Development and clinical evaluation of laser-sintered ankle foot orthoses. Plast Rubber Compos. 2018;47(1):42–6.

    CAS  Article  Google Scholar 

  27. Kerkum YL, Harlaar J, Buizer AI, van den Noort JC, Becher JG, Brehm M-A. An individual approach for optimizing ankle-foot orthoses to improve mobility in children with spastic cerebral palsy walking with excessive knee flexion. Gait Posture. 2016;46:104–11.

    Article  PubMed  Google Scholar 

  28. Meyns P, Kerkum YL, Brehm MA, Becher JG, Buizer AI, Harlaar J. Ankle foot orthoses in cerebral palsy: effects of ankle stiffness on trunk kinematics, gait stability and energy cost of walking. Eur J Paediatr Neurol. 2020;26:68–74.

    CAS  Article  PubMed  Google Scholar 

  29. Dufek JS, Neumann ES, Hawkins MC, O’Toole B. Functional and dynamic response characteristics of a custom composite ankle foot orthosis for Charcot-Marie-tooth patients. Gait Posture. 2014;39(1):308–13.

    Article  PubMed  Google Scholar 

  30. Bartonek Å, Eriksson M, Gutierrez-Farewik EM. A new carbon fibre spring orthosis for children with plantarflexor weakness. Gait Posture. 2007;25(4):652–6.

    Article  PubMed  Google Scholar 

  31. Bartonek Å, Eriksson M, Gutierrez-Farewik EM. Effects of carbon fibre spring orthoses on gait in ambulatory children with motor disorders and plantarflexor weakness. Dev Med Child Neurol. 2007;49(8):615–20.

    Article  PubMed  Google Scholar 

  32. Waterval NFJ, Brehm M-A, Altmann VC, Koopman FS, Den Boer JJ, Harlaar J, et al. Stiffness-optimized ankle-foot orthoses improve walking energy cost compared to conventional orthoses in neuromuscular disorders: a prospective uncontrolled intervention study. IEEE Trans Neural Syst Rehabil Eng. 2020;28(10):2296–304.

    Article  PubMed  Google Scholar 

  33. Waterval NFJ, Brehm M-A, Harlaar J, Nollet F. Individual stiffness optimization of dorsal leaf spring ankle–foot orthoses in people with calf muscle weakness is superior to standard bodyweight-based recommendations. J Neuroeng Rehabil. 2021;18(1):1–9.

    Article  Google Scholar 

  34. Arch ES, Reisman DS. Passive-dynamic ankle-foot orthoses with personalized bending stiffness can enhance net Plantarflexor function for individuals Poststroke. J Prosthetics Orthot. 2016;28(2):60–7.

    Article  Google Scholar 

  35. Kerkum YL, Philippart W, Houdijk H. The effects of footplate stiffness on push-off power when walking with posterior leaf spring ankle-foot orthoses. Clin Biomech. 2021;88:105422.

    CAS  Article  Google Scholar 

  36. Wojciechowski E, Chang AY, Balassone D, Ford J, Cheng TL, Little D, et al. Feasibility of designing, manufacturing and delivering 3D printed ankle-foot orthoses: a systematic review. J Foot Ankle Res. 2019;12(1):1–12.

    Article  Google Scholar 

  37. Shahar FS, Hameed Sultan MT, Shah AUM, Azrie Safri SN. A comparative analysis between conventional manufacturing and additive manufacturing of ankle-foot orthosis. Appl Sci Eng Prog. 2020;13(2):96–103.

    Article  Google Scholar 

  38. Telfer S, Pallari J, Munguia J, Dalgarno K, McGeough M, Woodburn J. Embracing additive manufacture: implications for foot and ankle orthosis design. BMC Musculoskelet Disord. 2012;13(1):1–9.

    Article  Google Scholar 

  39. Harper NG, Russell EM, Wilken JM, Neptune RR. Selective laser sintered versus carbon fiber passive-dynamic ankle-foot orthoses: a comparison of patient walking performance. J Biomech Eng. 2014;136(9):091001.

    Article  PubMed  Google Scholar 

  40. Ranz EC, Russell Esposito E, Wilken JM, Neptune RR. The influence of passive-dynamic ankle-foot orthosis bending axis location on gait performance in individuals with lower-limb impairments. Clin Biomech. 2016;37:13–21.

    Article  Google Scholar 

  41. Takahashi KZ, Stanhope SJ. Estimates of stiffness for ankle-foot orthoses are sensitive to loading conditions. J Prosthetics Orthot. 2010;22(4):211–9.

    Article  Google Scholar 

  42. Faustini MC, Neptune RR, Crawford RH, Stanhope SJ. Selective laser sintering of passive dynamic ankle-foot orthoses. 17th Solid Free. Fabr. Symp. SFF 2006; 2006. p. 124–9.

  43. Arch ES, Stanhope SJ. Passive-dynamic ankle–foot orthoses substitute for ankle strength while causing adaptive gait strategies: a feasibility study. Ann Biomed Eng. 2015;43(2):442–50.

    Article  PubMed  Google Scholar 

  44. Cha YH, Lee KH, Ryu HJ, Joo IW, Seo A, Kim DH, et al. Ankle-foot orthosis made by 3D printing technique and automated design software. Appl Bionics Biomech. 2017;2017:1–6.

    Article  Google Scholar 

  45. Kobayashi T, Leung AKL, Hutchins SW. Techniques to measure rigidity of ankle-foot orthosis: a review. J Rehabil Res Dev. 2011;48(5):565–76.

    Article  PubMed  Google Scholar 

  46. Ielapi A, Forward M, De Beule M. Computational and experimental evaluation of the mechanical properties of ankle foot orthoses: a literature review. Prosthetics Orthot Int. 2019;43(3):339–48.

    Article  Google Scholar 

  47. Cappa P, Patanè F, Di Rosa G. A continuous loading apparatus for measuring three-dimensional stiffness of ankle-foot orthoses. J Biomech Eng. 2005;127(6):1025–9.

    Article  PubMed  Google Scholar 

  48. Ielapi A, Lammens N, Van Paepegem W, Forward M, Deckers JP, Vermandel M, et al. A validated computational framework to evaluate the stiffness of 3D printed ankle foot orthoses. Comput Methods Biomech Biomed Engin. 2019;22(8):880–7.

    Article  PubMed  Google Scholar 

  49. Wach A, McGrady L, Wang M, Silver-Thorn B. Assessment of mechanical characteristics of ankle-foot orthoses. J Biomech Eng. 2018;140(7).

  50. Waterval NFJ, Nollet F, Harlaar J, Brehm MA. Modifying ankle foot orthosis stiffness in patients with calf muscle weakness: gait responses on group and individual level. J Neuroeng Rehabil. 2019;16(1):1–9.

    Article  Google Scholar 

  51. Vasiliauskaite E, Van Paepegem W, Deckers JP, Vermandel M, Forward M, Plasschaert F. Additive manufacturing of ankle-foot orthosis with predefined ankle stiffness - a case report. J Prosthetics Orthot. 2020;32(4):310–8.

    Article  Google Scholar 

  52. Li W, Lemaire ED, Baddour N. Design and evaluation of a modularized ankle-foot orthosis with quick release mechanism. 2020 42nd Annu. Int. Conf. IEEE Eng. Med. Biol. Soc., IEEE; 2020. p. 4831–4.

    Google Scholar 

  53. Surmen HK, Akalan NE, Fetvaci MC, Arslan YZ. A novel dorsal trimline approach for passive-dynamic ankle-foot orthoses. Strojniški Vestnik-J Mech Eng. 2018;64:185–94.

    Google Scholar 

  54. Zou D, He T, Dailey M, Smith KE, Silva MJ, Sinacore DR, et al. Experimental and computational analysis of composite ankle-foot orthosis. J Rehabil Res Dev. 2014;51(10):1525–36.

    Article  PubMed  PubMed Central  Google Scholar 

  55. Surmen HK, Akalan NE, Arslan YZ. Design, Manufacture, and Selection of Ankle-Foot-Orthoses. Encycl. Inf. Sci. Technol. Fourth Ed., IGI Global; 2018. p. 298–313.

    Google Scholar 

  56. Waterval NFJ, Brehm MA, Harlaar J, Nollet F. Energy cost optimized dorsal leaf ankle-foot-orthoses reduce impact forces on the contralateral leg in people with unilateral plantar flexor weakness. Gait Posture. 2021.

    Google Scholar 

  57. Lin CC, Yeh CH, Tsai YC, Kuo LC, Hsu HY, Chuang PH, et al. Evidence-based customized ankle-foot orthosis with energy storage. J Med Biol Eng. 2021;41(2):126–36.

    Article  Google Scholar 

  58. Meng X, Ren M, Zhuang Y, Qu Y, Jiang L, Li Z. Application experience and patient feedback analysis of 3D printed AFO with different materials: a random crossover study. Biomed Res Int. 2021;2021:1–6.

    CAS  Article  Google Scholar 

  59. Chae DS, Kim DH, Kang KY, Kim DY, Park SW, Park SJ, et al. The functional effect of 3D-printing individualized orthosis for patients with peripheral nerve injuries: three case reports. Medicine (Baltimore). 2020;99(16):e19791.

    Article  Google Scholar 

  60. Aldridge Whitehead JM, Russell Esposito E, Wilken JM. Stair ascent and descent biomechanical adaptations while using a custom ankle–foot orthosis. J Biomech. 2016;49(13):2899–908.

    Article  PubMed  Google Scholar 

  61. Kerkum YL, Buizer AI, Van Den Noort JC, Becher JG, Harlaar J, Brehm MA. The effects of varying ankle foot orthosis stiffness on gait in children with spastic cerebral palsy who walk with excessive knee flexion. PLoS One. 2015;10(11):e0142878.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  62. Lewallen J, Miedaner J, Amyx S, Sherman J. Effect of three styles of custom ankle foot orthoses on the gait of stroke patients while walking on level and inclined surfaces. J Prosthetics Orthot. 2010;22(2):78–83.

    Article  Google Scholar 

  63. Desloovere K, Molenaers G, Van Gestel L, Huenaerts C, Van Campenhout A, Callewaert B, et al. How can push-off be preserved during use of an ankle foot orthosis in children with hemiplegia? A prospective controlled study. Gait Posture. 2006;24(2):142–51.

    Article  PubMed  Google Scholar 

  64. Gök H, Küçükdeveci A, Altinkaynak H, Yavuzer G, Ergin S. Effects of ankle-foot orthoses on hemiparetic gait. Clin Rehabil. 2003;17(2):137–9.

    Article  PubMed  Google Scholar 

  65. Sienko Thomas S, Buckon CE, Jakobson-Huston S, Sussman MD, Aiona MD. Stair locomotion in children with spastic hemiplegia: the impact of three different ankle foot orthosis (AFOs) configurations. Gait Posture. 2002;16(2):180–7.

    Article  PubMed  Google Scholar 

  66. Burtner PA, Woollacott MH, Qualls C. Stance balance control with orthoses in a group of children with spastic cerebral palsy. Dev Med Child Neurol. 1999;41(11):748–57.

    CAS  Article  PubMed  Google Scholar 

  67. Rogati G, Leardini A, Ortolani M, Caravaggi P. Validation of a novel Kinect-based device for 3D scanning of the foot plantar surface in weight-bearing. J Foot Ankle Res. 2019;12(1):46.

    Article  PubMed  PubMed Central  Google Scholar 

  68. Highsmith MJ, Nelson LM, Carbone NT, Klenow TD, Kahle JT, Hill OT, et al. Outcomes associated with the intrepid dynamic exoskeletal orthosis (IDEO): a systematic review of the literature. Mil Med. 2016;181(S4):69–76.

    Article  PubMed  Google Scholar 

  69. Tagliaferri V, Trovalusci F, Guarino S, Venettacci S. Environmental and economic analysis of FDM, SLS and MJF additive manufacturing technologies. Materials (Basel). 2019;12(24):4161.

    CAS  Article  Google Scholar 

  70. Kafle A, Luis E, Silwal R, Pan HM, Shrestha PL, Bastola AK. 3D/4D printing of polymers: fused deposition modelling (FDM), selective laser sintering (SLS), and stereolithography (SLA). Polymers (Basel). 2021;13(18):3101.

    CAS  Article  Google Scholar 

  71. Bregman DJJ, Rozumalski A, Koops D, de Groot V, Schwartz M, Harlaar J. A new method for evaluating ankle foot orthosis characteristics: BRUCE. Gait Posture. 2009;30(2):144–9.

    CAS  Article  PubMed  Google Scholar 

  72. Totah D, Menon M, Gates DH, Barton K. Design and evaluation of the SMApp: a stiffness measurement apparatus for ankle–foot orthoses. Mechatronics. 2021;77:102572.

    Article  Google Scholar 

  73. Lai H-J, Yu C-H, Kao H-C, Chen W-C, Chou C-W, Cheng C-K. Ankle–foot simulator development for testing ankle–foot orthoses. Med Eng Phys. 2010;32(6):623–9.

    Article  PubMed  Google Scholar 

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The study is partially funded by the Italian 5 × 1000 funding scheme.

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GR contributed to the design of the study; revised the literature; classified the papers; helped with the interpretation of the results; wrote the first draft of the paper and contributed to the final revision process. PC helped to design the study; helped with the revision of the relevant literature; helped to organize the manuscript’s subsections; contributed to the writing of the first draft, and with the final revision process; helped with the critical analysis of the results.*- AL initiated the design of the study, organized and supported the work, analyzed the literature, helped with the preparation of the manuscript. The author(s) read and approved the final manuscript.

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Correspondence to Paolo Caravaggi.

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Rogati, G., Caravaggi, P. & Leardini, A. Design principles, manufacturing and evaluation techniques of custom dynamic ankle-foot orthoses: a review study. J Foot Ankle Res 15, 38 (2022).

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  • Ankle foot orthosis
  • Dynamic
  • Custom
  • Drop-foot
  • Additive manufacturing
  • 3D scanning
  • Functional evaluation
  • PD-AFO
  • Comfort, design