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Functional evaluation of patients treated with osteochondral allograft transplantation for post-traumatic ankle arthrosis


Osteochondral allograft ankle transplantation [1] seems to provide a very innovative and viable alternative for the treatment of post-traumatic ankle arthritis in selected individuals, mostly in young and active patients. The rationale behind this surgical procedure is essentially the transplantation of intact organ as hyaline articular cartilage, into a diseased or damaged area of the joint resulting in improved function [2]. The aim of our study was to evaluate functional outcome of young and active patients that underwent osteochondral allograft ankle transplantation by means of gait analysis.


Eight patients affected by grade III post-traumatic arthritis were assessed pre-operatively and at the mean follow-up of 12 months. In all cases a fresh osteochondral bipolar resurfacing of the ankle was performed. Clinical evaluations were performed according to the American Orthopaedic Foot and Ankle Society (AOFAS) score. All patients were also studied with gait analysis using the VICON (Oxford, UK) stereophotogrammetric system to evaluate kinematics data and two force platform (Kistler Instrumente AG, Switzerland) to evaluate ground reaction forces. Using electromyography (Zero Wire, Aurion) we analysed the bilateral activity of four muscles of lower limbs (rectus femoris, biceps femoris, gastrocnemius, tibialis anterior). Results were compared with those of a control group, consisting of 10 healthy subjects.


Clinical AOFAS score was significantly higher at twelve months after surgery (pre-surgery 43.8 ± 14.0; post-surgery 77.1 (7.8, p < 0.0005). Gait analysis showed a wider range of motion in the sagittal plane (increased maximum dorsiflexion in stance phase, plantarflexion at toe off, maximum plantarflexion in swing phase) and improved maximum vertical force at loading response after surgery. The EMG pattern of muscle activity became more physiological in the post-operative analysis, even if most patients showed the persistence of co-contractions of gastrocnemius and tibialis anterior muscles during the first half of the stance phase.


Short-term functional evaluation of the osteochondral allograft ankle transplantation showed satisfactory results for these patients. The integrated gait analysis revealed only few abnormalities in kinematics, kinetics, and EMG. The persisting tibialis anterior activity during stance could be related to proprioception deficit and could be improved by time and exercise. It will be important to re-evaluate these patients also at longer follow-ups in order to confirm these positive results.


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Correspondence to MG Benedetti.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Berti, L., Benedetti, M., Vannini, F. et al. Functional evaluation of patients treated with osteochondral allograft transplantation for post-traumatic ankle arthrosis. J Foot Ankle Res 1 (Suppl 1), O52 (2008).

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