Table 3 Time until finally achieving 95% granulation of the study wound and treatment continuation after optimal preparation for further therapeutic measures within 16 weeks in the PP population

Study participants in the PP population, No.

44

110

NA

Study participants without achieving 95% granulation of the study wound, No. (%)

8 (18.2%)

54 (49.1%)

< 0.001 (Chi-squared)

Study participants with achieving 95% granulation of the study wound, No. (%)

36 (81.8%)

56 (50.9%)

 Mean (SD)

33.9 (30.6)

62.0 (37.4)

0.003 (U)

 [95% CI]

[21.8-46.0]

[50.8-73.3]

 Min-Max

0 – 111

0 - 115

Study participants without data after 95% granulation of the study wound, No. (%)

0 of 36 (0)

15 of 56 (26.8)

NA

Study participants with data after 95% granulation of the study wound, No. (%)

36 of 36 (100)

41 of 56 (73.2)

NA

Study participants with SMWC after 95% granulation of the study wound, No. (%)

32 of 36 (88.9)

35 of 41 (85.4)

NA

 Mean (SD)

61.3 (32.5)

65.5 (36.2)

0.411 (U)

 Min-Max

14 – 107

1 – 112

 Study participants with data available, No.

13

17

 Mean (SD)

19.2 (13.9)

12.7 (9.1)

0.145 (U)

 Min-Max

6 – 56

1 – 35

 Study participants with data available, No.

31

34

 Mean (SD)

55.8 (32.7)

61.6 (33.9)

0.412 (U)

 Min-Max

2 – 107

1 – 112