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Table 2 Summary of final panel judgements compared with the IWGDF judgements for all the IWGDF Offloading recommendations

From: Australian guideline on offloading treatment for foot ulcers: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease

No. Problem Desirable effects Undesirable effects Quality of evidence Values Balance of effects Acceptability Applicability/ feasibility Decision Comments
1a +
Yes
?
Moderate
+
Trivial
-
Moderate
+
Probably no important uncertainty
+
Favours the intervention
+
Probably yes
+
Probably yes
Adapt Adapted QoE & control
1b +
Yes
?
Trivial
+
Trivial
-
Low
+
Probably no important uncertainty
+
Does not favour either intervention or control
+
Probably yes
+
Probably yes
Adapt Adapted QoE & strength of recommendation
2 +
Yes
+
Moderate
?
Varies
+
Low
-
Possibly important uncertainty
+
Probably favours the intervention
+
Varies
+
Probably yes
Adapt Adapted control, patient circumstances & foot-device interface
3 +
Yes
?
Varies
+
Small
-
Very low
+
Probably no important uncertainty
+
Favours the intervention
+
Yes
+
Yes
Adapt Adapted QoE, control, patient circumstances & foot-device interface
4a +
Yes
?
Don’t know
?
Don’t know
-
Low
-
Possibly important uncertainty
+
Favours the comparison
+
Probably yes
+
Probably yes
Adapt Adapt QoE & control
4b + Yes + Small + Small - Very low + Probably no important uncertainty + Probably favours the intervention + Probably yes + Probably yes Adapt Adapted QoE, intervention & control
5 +
Yes
+
Moderate
+
Small
+
Low
+
Probably no important uncertainty
+
Probably favours the intervention
+
Probably yes
?
Probably yes
Adapt Adapted intervention
6 +
Probably
yes
+
Moderate
+
Small
+
Low
+
Probably no important uncertainty
+
Probably favours the intervention
+
Probably yes
?
Yes
Adapt Adapted population
7a = = = = = = = = Adopt Adopted in screening
7b = = = = = = = = Adopt Adopted in screening
7c = = = = = = = = Adopt Adopted in screening
8 = = = = = = = = Adopt Adopted in screening
9 +
Yes
-
Don’t know
-
Don’t know
-
Very low
+
Probably no important uncertainty
+
Favours the intervention
+
Probably yes
+
Probably yes
Adapt Adapted QoE, intervention & control
  1. Note: +, panel agreed with the original IWGDF judgement; −, panel disagreed with the original IWGDF judgement; ?, panel unsure if agreed with the original IWGDF judgement due to lack of IWGDF information on judgement; =, panel agreed with the original IWGDF judgement during screening (see Table 1); QoE Quality of evidence