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Table 2 Cox regression analysis of variables associated with amputation

From: Rates and risk factors for amputation in people with diabetes in Japan: a historical cohort study using a nationwide claims database

 

Univariate analysis

P-value

Multivariate analysis

P-value

HR (95% CI)

HR (95% CI)

Age (years)

1.08 (1.02–1.16)

0.01

1.09 (1.02–1.16)

0.01

 Sex

1.40 (0.32–6.17)

0.66

 

 BMI 1 kg/m2 increase

0.98 (0.88–1.10)

0.74

 

 SBP 10 mmHg increase

1.13 (0.86–1.47)

0.39

 

DBP 5 mmHg increase

0.79 (0.63–0.99)

0.04

0.81 (0.64–1.01)

0.07

 LDL-cholesterol 1 mmol/L increase

1.42 (0.85–2.37)

0.18

 

 HDL-cholesterol 1 mmol/L increase

0.67 (0.17–2.63)

0.56

 

 Current smoking

1.25 (0.46–3.35)

0.66

 

HbA1c (%)

1.38 (1.11–1.71)

< 0.01

1.46 (1.17–1.81)

< 0.01

  1. BMI body mass index, DBP diastolic blood pressure, SBP systolic blood pressure, HR hazard ratio, CI confidence interval, LDL low-density lipoprotein, HDL high-density lipoprotein, HbA1c glycated hemoglobin