Table 1 Baseline characteristics of study participants according to the presence or absence of lower limb amputation
Characteristic cardiovascular manifestation in FH Kawaguchi et al. Am Heart J 1999 | Lower limb amputation | P-value | |
|---|---|---|---|
(−) | (+) | ||
n = 17,272 | n = 16 | ||
Age (years) | 50 ± 8 | 54 ± 10 | 0.025 |
≥60 (%) | 2137(12) | 6 (38) | 0.002 |
Sex (men, %) | 14,322 (83) | 14 (88) | 0.630 |
BMI (kg/m2) | 26.1 ± 4.6 | 25.7 ± 5.4 | 0.768 |
SBP (mmHg) | 130 ± 17 | 134 ± 25 | 0.556 |
DBP (mmHg) | 80 ± 11 | 75 ± 14 | 0.050 |
HbA1c (%) | 7.2 ± 1.4 | 8.3 ± 2.1 | 0.054 |
HbA1c IFCC (mmol/mol) | 55 ± 16 | 67 ± 23 | 0.054 |
HbA1c ≥8.0 (%) | 3542(21) | 8 (50) | 0.004 |
LDL-cholesterol (mmol/L) | 3.3 ± 0.9 | 3.6 ± 1.5 | 0.449 |
HDL-cholesterol (mmol/L) | 1.4 ± 0.4 | 1.4 ± 0.4 | 0.546 |
Current smoking (%) | 6498 (38) | 7 (44) | 0.613 |