|
Characteristic cardiovascular manifestation in FH Kawaguchi et al. Am Heart J 1999
|
Lower limb amputation
|
P-value
|
|---|
|
(−)
|
(+)
|
|---|
|
n = 17,272
|
n = 16
|
|---|
|
Age (years)
|
50 ± 8
|
54 ± 10
|
0.025
|
|
≥60 (%)
|
2137(12)
|
6 (38)
|
0.002
|
|
Sex (men, %)
|
14,322 (83)
|
14 (88)
|
0.630
|
|
BMI (kg/m2)
|
26.1 ± 4.6
|
25.7 ± 5.4
|
0.768
|
|
SBP (mmHg)
|
130 ± 17
|
134 ± 25
|
0.556
|
|
DBP (mmHg)
|
80 ± 11
|
75 ± 14
|
0.050
|
|
HbA1c (%)
|
7.2 ± 1.4
|
8.3 ± 2.1
|
0.054
|
|
HbA1c IFCC (mmol/mol)
|
55 ± 16
|
67 ± 23
|
0.054
|
|
HbA1c ≥8.0 (%)
|
3542(21)
|
8 (50)
|
0.004
|
|
LDL-cholesterol (mmol/L)
|
3.3 ± 0.9
|
3.6 ± 1.5
|
0.449
|
|
HDL-cholesterol (mmol/L)
|
1.4 ± 0.4
|
1.4 ± 0.4
|
0.546
|
|
Current smoking (%)
|
6498 (38)
|
7 (44)
|
0.613
|
- Data are presented as n (%), mean ± SD. BMI body mass index, HbA1c IFCC glycated hemoglobin, International Federation of Clinical Chemistry and Laboratory Medicine units, SBP systolic blood pressure, DBP diastolic blood pressure, LDL-C low-density lipoprotein-cholesterol, HDL-C high-density lipoprotein-cholesterol
