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Table 2 Patients categorized into re-amputation and non-reamputation

From: Re-amputation in patients with diabetes-related minor amputations who underwent physical therapy during their hospitalization

Characteristics Total
(n=129)
Re-amputation group
(n =42)
Non-reamputation group
(n =87)
p value
Age (years) 66.2 ± 12.3 66.7 ± 12.6 66.0 ± 12.3 0.75
Sex, male, n (%) 83 (64.3) 30 (71.4) 53 (60.9) 0.18
BMI (kg/m2) 22.9 ± 2.3 22.7 ± 2.8 23.0 ± 2.5 0.69
Hospitalization days 33.4 ± 15.7 36.2 ± 16.5 34.3 ± 18.1 0.41
Physical therapy period (days) 23.0 ± 9.2 22.6 ± 9.3 23.1 ± 9.2 0.79
Length of daily physical therapy (min) 40.2 ± 14.8 41.5 ± 7.8 39.6 ± 10.3 0.63
Non-weight-bearing period (days) 15(11–20) 15 (11–20) 17 (12–20) 0.71
Comorbidities, n (%)
 Hypertension 64 (49.6) 22 (52.3) 42 (48.2) 0.53
 Heart disease 40 (31.0) 12 (28.5) 28 (32.1) 0.65
 Cerebrovascular disease 6 (0.4) 2 (4.2) 4 (4.5) 0.41
 COPD 4 (0.2) 1 (2.1) 3 (3.4) 0.98
 Hemodialysis 41 (31.7) 19 (40.4) 22 (25.2) <0.01
Laboratory parameters
 Serum albumin (g/dL) 2.7 ± 1.1 2.6 ± 1.0 2.8 ± 1.1 0.52
 Serum hemoglobin (g/dL) 11.4 ± 2.2 11.1 ± 1.9 11.9 ± 2.3 0.09
 Blood glucose 183.6 ± 19.3 179.7 ± 17.4 187.2 ± 21.8 0.19
 CRP ( mg/dl) 0.4 ± 1.1 0.5 ± 1.4 0.7 ± 0.9 0.35
 WBC 103/μL 9435.9 ± 3203.6 9154.7 ± 3069.3 9573.2 ± 3276.0 0.44
eGFR ( mL/min/1.73 m2) , n (%)
 eGFR ≥60 39 (30.2) 12 (28.5) 27 (31.0) 0.91
 eGFR 45–59 14 (10.8) 4 (9.5) 10 (11.4)
 eGFR 30–44 17 (13.1) 5 (11.9) 12 (13.7)
 eGFR < 30 59 (45.7) 21 (50.0) 38 (43.6)
Lower l imb blood flow
 SPP (mmHg) 36.7 ± 14.6 35.9 ± 14.2 37.1 ± 14.8 0.58
 ABI 0.5 ± 0.2 0.6 ± 0.2 0.5 ± 0.3 0.15
WIfI classification, n (%)
 W0 23 (17.8) 8 (19.0) 19 (21.8) 0.81
 W1 35 (27.1) 13 (30.9) 27 (31.0)
 W2 41 (31.7) 11 (26.1) 19 (21.8)
 W3 46 (35.6) 10 (23.8) 22 (25.2)
Amputation region, n (%)
 Toe amputation 63 (48.8) 22 (52.3) 41 (47.1) 0.06
 Ray amputation 42 (32.5) 13 (30.9) 29 (33.3) 0.51
 Transmetatarsal amputation 24 (18.6) 7 (16.6) 17 (19.5) 0.34
Foot deformation, n (%)
 Charcot's joint 12 (9.3) 4 (8.5) 8 ( 9.1) 0.97
 Hallux valgus 19 (14.7) 7 (14.8) 12 (13.7) 0.68
 Hammer toe 17 (13.1) 7 (14.8) 10 (11.4) 0.24
 Claw toe 19 (14.7) 8 (17.0) 11 (12.6) 0.35
Physical function
 Knee Extension Muscle Strength (kef) 20.4 ± 6.1 19.2 ± 5.8 21.0 ± 6.2 0.11
 Ankle dorsiflexion angle (°) 6.4 ± 8.5 2.6 ± 9.2 8.3 ± 7.6 <0.01
 Ankle plantar flexion angle (°) 17.5 ± 11.5 16.7 ± 11.9 17.8 ± 11.7 0.61
 Plantar Sensory disorder, n (%) 94 (72.8) 32 (76.1) 62 (71.2) 0.62
 FIM ambulation score 5 (4–6) 6 (5–7) 5 (4–6) <0.01
  1. Data expressed as mean ± standard deviation, median (interquartile range), n (%). BMI Body mass index, COPD Chronic obstructive pulmonary disease, CRP C-reactive protein, WBC White blood cell, SPP Skin perfusion pressure, ABI Ankle brachial pressure index, FIM Functional Independence Measure