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Table 4 Rank data and significance for the Wilcoxon signed-rank tests for VAS average pain. A negative rank represents an improvement in a patient’s pain over that time period. A positive rank represents worsening pain over that time period

From: The effectiveness of PROLOTHERAPY for recalcitrant Medial TIBIAL Stress Syndrome: a prospective consecutive CASE series

Time period Ranks N p-value
Baseline – 4 weeks
(n = 18)
Negative ranks 16 < 0.001
Positive ranks 1  
Ties 1  
Baseline – 18 weeks Negative ranks 16 < 0.001
(n = 18) Positive ranks 0  
Ties 2  
4 weeks – 18 weeks Negative ranks 5 0.405
(n = 18) Positive ranks 7  
Ties 6  
Baseline – 52 weeks Negative ranks 13 0.001
(n = 15) Positive ranks 1  
Ties 1  
4 weeks – 52 weeks Negative ranks 5 0.322
(n = 15) Positive ranks 6  
Ties 4