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Table 2 Top 10 SNPs from meta-analysis, adjusted for sex, BMI, age, study site, and principal components (total sample, N = 5925)

From: Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians

SNP rsID Chr:Position Nearest Gene EA/OA EAF OR (95% CI) P-value Direction I2 Het. P-value P-value sens.
rs55807512 1:86916200 CLCA2 t/c 0.96 0.48 (0.38, 0.61) 2.96E-09 0 0.67 4.75E-10
rs12124247 1:86890244 CLCA2 a/g 0.03 2.19 (1.68, 2.86) 7.38E-09 ++++ 0 0.68 2.39E-09
rs146496015 1:86799387 ODF2L t/g 0.06 1.61 (1.34, 1.94) 3.14E-07 ++++ 1.6 0.38 5.25E-07
rs12888772 14:81578926 RP11-114 N19.3 a/t 0.18 1.30 (1.17, 1.44) 7.92E-07 ++++ 0 0.96 1.55E-07
rs117155606 17:54325272 ANKFN1 t/c 0.01 5.53 (2.78, 11.02) 1.13E-06 ? +??? 0 1 1.13E-06
rs11728629 4:126712045 RP11-404I7.1 a/t 0.24 1.26 (1.15, 1.38) 1.28E-06 ++++ 0 0.8 1.32E-05
rs4314298 4:126710287 RP11-404I7.1 a/g 0.76 0.80 (0.73, 0.87) 1.42E-06 0 0.82 1.52E-05
rs116783165 5:25669440 CTD-2533 K21.1 c/g 0.03 1.72 (1.37, 2.15) 1.95E-06 ++++ 58.6 0.06 5.56E-06
rs116336450 5:25663890 CTD-2533 K21.1 t/c 0.97 0.58 (0.47, 0.73) 2.13E-06 60.5 0.06 5.87E-06
rs79433053 5:25668523 CTD-2533 K21.1 t/c 0.03 1.71 (1.37, 2.14) 2.17E-06 ++++ 60.3 0.06 5.98E-06
  1. Chr Chromosome, EA Effect allele, OA Other allele, OR Odds ratio, CI Confidence interval, Het Heterogeneity, sens Sensitivity
  2. Intron SNPs are indicated in bold