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Table 2 Top 10 SNPs from meta-analysis, adjusted for sex, BMI, age, study site, and principal components (total sample, N = 5925)

From: Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians

SNP rsIDChr:PositionNearest GeneEA/OAEAFOR (95% CI)P-valueDirectionI2Het. P-valueP-value sens.
rs558075121:86916200CLCA2t/c0.960.48 (0.38, 0.61)2.96E-0900.674.75E-10
rs121242471:86890244CLCA2a/g0.032.19 (1.68, 2.86)7.38E-09++++00.682.39E-09
rs1464960151:86799387ODF2Lt/g0.061.61 (1.34, 1.94)3.14E-07++++1.60.385.25E-07
rs1288877214:81578926RP11-114 N19.3a/t0.181.30 (1.17, 1.44)7.92E-07++++00.961.55E-07
rs11715560617:54325272ANKFN1t/c0.015.53 (2.78, 11.02)1.13E-06? +???011.13E-06
rs117286294:126712045RP11-404I7.1a/t0.241.26 (1.15, 1.38)1.28E-06++++00.81.32E-05
rs43142984:126710287RP11-404I7.1a/g0.760.80 (0.73, 0.87)1.42E-0600.821.52E-05
rs1167831655:25669440CTD-2533 K21.1c/g0.031.72 (1.37, 2.15)1.95E-06++++58.60.065.56E-06
rs1163364505:25663890CTD-2533 K21.1t/c0.970.58 (0.47, 0.73)2.13E-0660.50.065.87E-06
rs794330535:25668523CTD-2533 K21.1t/c0.031.71 (1.37, 2.14)2.17E-06++++60.30.065.98E-06
  1. Chr Chromosome, EA Effect allele, OA Other allele, OR Odds ratio, CI Confidence interval, Het Heterogeneity, sens Sensitivity
  2. Intron SNPs are indicated in bold