From: Research on lower extremity health in patients with multiple sclerosis: a systematic scoping review
| Measurement focus | Data collection method | References |
|---|---|---|
| Gait (biomechanics) | 3D or visual gait analysis of gait parameters (e.g. step width, swing, stride length) | [46, 54,55,56, 59, 67,68,69,70, 73, 76, 77, 79, 84] |
| Fast walking speed | [48, 53] | |
| Gait (ability) | 2-min walk test | [49, 53, 58, 59, 61] |
| 10-m walk test | [18, 70] | |
| 5-min walk test | [74] | |
| Stair climb test | [18, 61] | |
| Bessou’s locometer | [81] | |
| Multiple Sclerosis Walking Scale (self-reported) | [58, 65, 67, 72, 74, 81] | |
| Mobility | Timed up-and-go test | [18, 48, 49, 52, 58, 59, 70, 81] |
| Timed 25-ft walk | [44, 48, 49, 54, 58,59,60,61, 65, 74, 77, 79, 81, 83] | |
| 500-m walk | [77] | |
| Aerobic capacity and endurance | 6-min walk test | [18, 45, 58, 62, 63, 70, 79, 81] |
| One-legged cycling test | [62] | |
| Physical activity | International Physical Activity Questionnaire | [67] |
| Muscle strength | Isokinetic dynamometry | [49, 55, 61] |
| Isometric dynamometry | [18, 51, 57, 61,62,63,64, 77, 79] | |
| Dynamometer | [54, 82, 83] | |
| Sit to stand (5 times) | [61] | |
| Muscle endurance | Number of repetitions on seated leg press | [53] |
| 3-min stepping test | [55] | |
| Muscle stiffness and spasticity | Multiple Sclerosis Spasticity Scale | [53] |
| Ashworth Scale | [50, 71, 81] | |
| Tardieu Scale | [71] | |
| Functional ambulatory score | [65] | |
| Resistance to passive range of motion | [75] | |
| Tendon reflexes | [75] | |
| Dynamic or passive range of motion | [68, 69, 76] | |
| Balance | Stabilometry or posturography | [48, 54, 63, 72] |
| Obstacle negotiation | [70] | |
| Timed standing on one leg | [50, 51] | |
| Static postural control | [58] | |
| Centre of pressure | [52, 79] | |
| Activities-specific Balance Confidence Scale | [67, 74, 81] | |
| Berg Balance Scale | [18, 49, 80, 81] | |
| Specific foot assessments | Vibration perception | [50, 54, 60] |
| Force distribution | [66, 78] | |
| Plantar pressure | [66, 78] | |
| Neuropathic pain | [60] | |
| Sudomotor function | [60] | |
| Oedema: Fovea’s sign, Stemmer’s sign | [80] | |
| Sensation: Semmes-Weinstein monofilament | [50] | |
| Foot deformities | [75] |