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Table 1 Baseline characteristics of diabetic foot ulcer patients in the two age groups

From: Phenotypes and outcomes in middle-aged patients with diabetic foot ulcers: a retrospective cohort study

 All
(N = 422)
Middle-aged
(N = 175)
Elderly
(N = 247)
P
Demographics
 Age (years)66.2 ± 12.054.5 ± 8.074.4 ± 6.1<0.001
 Gender (male/female)265/157116/59149/980.212
 BMI (kg/m2)22.6 ± 2.922.4 ± 3.122.8 ± 2.80.190
 Alcohol consumption (yes/no)128/29467/10861/1860.004
 Smoking habit (yes/no)149/27376/9973/1740.004
Diabetic history
 Diabetes type (type1/type 2)8/4148/1670/2470.001
 Diabetic duration (years)9.7 ± 7.77.9 ± 6.211.0 ± 8.4<0.001
 Treatment: no treatment/oral drugs/insulin32/160/23022/59/9612/101/1340.027
Laboratory test
 Fastingplasma glucose (mmol/L)11.4 ± 5.412.2 ± 6.010.9 ± 4.90.017
 HbA1c (%)9.2 ± 2.49.6 ± 2.88.2 ± 2.10.003
 Haemoglobin (g/l)115 (102–129)118 (100–129)114 (103–129)0.894
 Serum albumin (g/l)34.3 ± 6.234.1 ± 6.734.5 ± 5.80.512
 White blood cells (103/l)8.7 ± 4.48.9 ± 5.18.57 ± 3.80.482
 eGFR (mL/min/1.73 m2)74.9 ± 28.886.7 ± 30.266.5 ± 24.5<0.001
 Total cholesterol (mmol/L)4.0 ± 1.14.0 ± 1.04.1 ± 1.00.325
 Triglycerides (mmol/L)1.4 ± 0.71.3 ± 0.71.4 ± 0.70.194
 LDL cholesterol (mmol/L)2.3 ± 0 .82.3 ± 0 .92.3 ± 0.80.377
 HDL cholesterol (mmol/L)1.1 ± 0 .31.1 ± 0 .41.1 ± 0 .30.686
Comorbidities
 Hypertension (yes/no)273/14989/86184/63<0.001
 Coronary heart disease (yes/no)69/35316/15953/1940.001
 History of stroke (yes/no)44/3786/16938/209<0.001
Diabetic complication
 Nephropathy (yes/no)176/24668/107108/1390.318
 Peripheral artery disease (1/2/3)211/127/84120/36/1991/91/65<0.001
 Retinopathy (yes/no)125/29764/11161/1860.008
 Peripheral neuropathy (yes/no)313/109139/36174/730.042
Ulcer characteristics
 Duration of ulcer (days)57.6 ± 78.654.5 ± 77.256.3 ± 79.70.815
 Extent (cm2)8.1 ± 16.010.5 ± 21.56.4 ± 10.300.019
 Depth (1/2/3)97/249/7643/91/4154/158/350.021
 Infection (1/2/3/4)18/245/130/296/108/49/1212/137/81/170.584
 Debridement (yes/no)155/26767/10888/1590.609
 Antibiotics (≤ 1/≥ 2)247/17592/83155/920.045
 Revascularization (yes/no)47/35710/16537/2100.003