Table 2 NHMRC levels of evidence and modified McMaster results of methodological quality
From: The use of urea for the treatment of onychomycosis: a systematic review
Study | NHMRC level and study design | Items on modified McMaster critical review form | Raw score and % | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3a | 3b | 3c | 3d | 3e | 4a | 4b | 5a | 5b | 5c | 6a | 6b | 6c | 6d | 7 | |||
Bassiri -Jahromi et al. 2012 [30] | Level II-RCT | Y | N | Y | N | Y | N | Y | N | N | Y | N | Y | N | Y | N | Y | N | 8/17 47.06% |
Lahfa et al. 2013 [31] | Level II-RCT | Y | Y | Y | Y | Y | Y | Y | N | N | Y | Y | Y | Y | Y | N | Y | Y | 14/17 82.35% |
Bunyaratavej at al. 2016 [32] | Level III-2 Case-control | Y | Y | Y | N | N | NA | Y | N | N | Y | Y | Y | Y | Y | N | NA | Y | 10/15 66.60% |
Fraki et al. 1997 [33] | Level III-3 Comparative study without controls | Y | Y | Y | N | Y | N | Y | N | N | Y | Y | N | Y | N | N | Y | Y | 10/17 58.82% |
Escalante et al. 2013 [34] | Level III-3 Comparative study without controls | Y | Y | Y | N | Y | Y | Y | N | N | Y | Y | N | Y | Y | N | Y | Y | 12/17 70.59% |
Baran and Tosti 2002 [35] | Level IV Case-series | N | Y | Y | N | NA | NA | Y | N | N | N | N | N | N | N | N | NA | Y | 4/14 28.57% |