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Table 9 Overview of studies which compared SSI rates in cohorts which received and did not receive antibiotic prophylaxis

From: Antibiotic prophylaxis in foot and ankle surgery: a systematic review of the literature

Study

# Participants

Incidence of SSI

Overview

Antibiotic Prophylaxis

No Antibiotic Prophylaxis

Study Design

Level of Evidence

Butterworth et al. (2017) [18]

4238

1.1%

2.6%

Prospective Cohort Study

2++

Mangwani et al. (2016) [27]

100

6.2%

1.9%

Prospective RCT

1++

Reyes et al. (1997) [37]

459

0.43%

0.88%

Retrospective Cohort Study

3

Zgonis et al. (2004) [22]

555

1.6%

1.4%

Retrospective Cohort Study

2+