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Table 5 Classification of evidence based on NICE protocol [2]

From: Antibiotic prophylaxis in foot and ankle surgery: a systematic review of the literature

Study Study Design Level of Evidence
Akinyoola et al. (2011) [19] Prospective RCT 1-
Butterworth et al. (2017) [18] Prospective Cohort Study 2++
Dayton et al. (2015) [34] Consensus Panel (Expert Opinion) 4
Deacon et al. (1996) [20] Prospective Cohort Study 2++
Dounis et al. (1995) [21] Prospective Cohort Study 2-
Kurup (2016) [35] Retrospective Cohort Study (Abstract Only) 4
Mangwani et al. (2016) [27] Prospective RCT 1++
Pace et al. (2016) [36] National Survey 4
Reyes et al. (1997) [37] Retrospective Comparative Study 3
Tantigate et al. (2016) [28] Retrospective Comparative Study 3
Zgonis et al. (2004) [22] Retrospective Cohort Study 2+