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Table 5 Classification of evidence based on NICE protocol [2]

From: Antibiotic prophylaxis in foot and ankle surgery: a systematic review of the literature

Study

Study Design

Level of Evidence

Akinyoola et al. (2011) [19]

Prospective RCT

1-

Butterworth et al. (2017) [18]

Prospective Cohort Study

2++

Dayton et al. (2015) [34]

Consensus Panel (Expert Opinion)

4

Deacon et al. (1996) [20]

Prospective Cohort Study

2++

Dounis et al. (1995) [21]

Prospective Cohort Study

2-

Kurup (2016) [35]

Retrospective Cohort Study (Abstract Only)

4

Mangwani et al. (2016) [27]

Prospective RCT

1++

Pace et al. (2016) [36]

National Survey

4

Reyes et al. (1997) [37]

Retrospective Comparative Study

3

Tantigate et al. (2016) [28]

Retrospective Comparative Study

3

Zgonis et al. (2004) [22]

Retrospective Cohort Study

2+