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Table 11 Use of Antibiotics in studies meeting the inclusion criteria and their administration protocol where defined

From: Antibiotic prophylaxis in foot and ankle surgery: a systematic review of the literature

Study Antibiotic Agent(s) Dose Route Timing
Akinyoola et al. (2011) [19] Cefuroxime Not stated IV 5 min prior or 1 min following tourniquet inflation as well as 3 doses postoperative at 8 h intervals
Butterworth et al. (2017) [18] Not stated Not stated Not stated Not stated
Dayton et al. (2015) [34] N/A N/A N/A N/A
Deacon et al. (1996) [20] Cefazolin 1 g IV 34–60 min prior to incision
Dounis et al. (1995) [21] Ceftazidimine or Ceftriaxone 2 g IV 10–240 min prior to inflation of tourniquet
Kurup (2016) [35] Teicoplanin 400 mg IV Not stated
Mangwani et al. (2016) [27] Flucloxacillin or Teicoplanin Not stated Not stated Not stated
Pace et al. (2016) [36] N/A N/A N/A N/A
Reyes et al. (1997) [37] Cefazolin or Vancomycin Not stated IV 30–60 min according to manufactures guidance prior to incision
Tantigate et al. (2016) [28] Cefazolin, Clindamycin or Vancomycin Not stated IV 0–60 min prior to incision
Zgonis et al. (2004) [22] Not stated Not stated IV 0–120 min prior to incision