Skip to main content

Table 3 Multivariate logistic regression analysis of risk factors to predict major LEA in the patients with infectious foot gangrene

From: Survival and associated risk factors in patients with diabetes and amputations caused by infectious foot gangrene

Factors+

Interpretation

Odds ratio

95% confidence interval

P value

Abnormal ABI

Yes vs. No

3.12*

1.18–8.24

0.02

Age

Every 1 year increment

0.97

0.93–1.02

0.21

Diabetes duration

Every 1 year increment

0.99

0.94–1.04

0.66

Smoking status

Yes vs. No

0.54

0.19–1.53

0.25

Hypertension

Yes vs. No

1.28

0.53–3.10

0.59

MACE history

Yes vs. No

1.13

0.45–2.80

0.80

CKD (eGFR < 60)

vs. normal renal function (eGFR ≥60)

1.81

0.74–4.46

0.20

Dialysis

vs. normal renal function (eGFR ≥60)

2.51

0.71–8.85

0.15

HbA1c

Every 1% increment

0.95

0.81–1.13

0.58

  1. *Significance: P value <0.05
  2. +Including the continuous variable of age, diabetes duration and HbA1c; and categorical variables of smoking status, hypertension, major adverse cardiac events, ankle-brachial index, and renal function
  3. LEA lower-extremity amputation, ABI ankle-brachial index, MACE major adverse cardiac event, CKD chronic kidney disease, eGFR estimated glomerular filtration rate