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Table 3 Multivariate logistic regression analysis of risk factors to predict major LEA in the patients with infectious foot gangrene

From: Survival and associated risk factors in patients with diabetes and amputations caused by infectious foot gangrene

Factors+ Interpretation Odds ratio 95% confidence interval P value
Abnormal ABI Yes vs. No 3.12* 1.18–8.24 0.02
Age Every 1 year increment 0.97 0.93–1.02 0.21
Diabetes duration Every 1 year increment 0.99 0.94–1.04 0.66
Smoking status Yes vs. No 0.54 0.19–1.53 0.25
Hypertension Yes vs. No 1.28 0.53–3.10 0.59
MACE history Yes vs. No 1.13 0.45–2.80 0.80
CKD (eGFR < 60) vs. normal renal function (eGFR ≥60) 1.81 0.74–4.46 0.20
Dialysis vs. normal renal function (eGFR ≥60) 2.51 0.71–8.85 0.15
HbA1c Every 1% increment 0.95 0.81–1.13 0.58
  1. *Significance: P value <0.05
  2. +Including the continuous variable of age, diabetes duration and HbA1c; and categorical variables of smoking status, hypertension, major adverse cardiac events, ankle-brachial index, and renal function
  3. LEA lower-extremity amputation, ABI ankle-brachial index, MACE major adverse cardiac event, CKD chronic kidney disease, eGFR estimated glomerular filtration rate