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Table 2 Clinical characteristics of the patients with diabetes and infectious foot gangrene with different LEA status

From: Survival and associated risk factors in patients with diabetes and amputations caused by infectious foot gangrene

Characteristic Mean (standard deviation) or Number (%)
Minor LEA (n = 67) Major LEA (n = 90) P value
Death 38 48  
Median survival time (years) 5.5 (95% CI: 2.58–8.42) 1.9 (95% CI: 1.15–2.65) <0.01*
5-year survival rate 54% 30%  
Age (years) 65.8 (±11.7) 67.6 (±10.1) 0.32
Gender      0.56
 Female 23 (34.3%) 35 (38.9%)  
 Male 44 (65.7%) 55 (61.1%)  
Diabetes duration (years) 11.9 (±8.9) 13.5 (±8.1) 0.24
Smoking status 18 (26.9%) 16 (17.8%) 0.17
Hypertension 44 (65.7%) 67 (74.4%) 0.23
Major adverse cardiac events 17 (25.4%) 35 (38.9%) 0.08
Abnormal ABI 32 (47.8%) 72 (80.0%) <0.01*
Renal function      0.09
 Normal renal function (eGFR ≥60) 31 (46.3%) 27 (30.0%)  
 Chronic kidney disease (eGFR <60) 23 (34.3%) 36 (40.0%)  
 Dialysis 13 (19.4%) 27 (30.0%)  
HbA1c (%) 9.7 (±2.5) 9.0 (±2.9) 0.14
Hospitalization duration (days) 48.2 (±34.7) 36.9 (±25.2) 0.03*
  1. *Significance: P value <0.05
  2. +Including continuous variables of age and diabetes duration; and categorical variables of gender, smoking status, hypertension, major adverse cardiac events, ankle-brachial index, and renal function
  3. LEA lower-extremity amputation, ABI ankle-brachial index, eGFR estimated glomerular filtration rate