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Table 2 Clinical characteristics of the patients with diabetes and infectious foot gangrene with different LEA status

From: Survival and associated risk factors in patients with diabetes and amputations caused by infectious foot gangrene

Characteristic

Mean (standard deviation) or Number (%)

Minor LEA

(n = 67)

Major LEA

(n = 90)

P value

Death

38

48

 

Median survival time (years)

5.5 (95% CI: 2.58–8.42)

1.9 (95% CI: 1.15–2.65)

<0.01*

5-year survival rate

54%

30%

 

Age (years)

65.8

(±11.7)

67.6

(±10.1)

0.32

Gender

    

0.56

 Female

23

(34.3%)

35

(38.9%)

 

 Male

44

(65.7%)

55

(61.1%)

 

Diabetes duration (years)

11.9

(±8.9)

13.5

(±8.1)

0.24

Smoking status

18

(26.9%)

16

(17.8%)

0.17

Hypertension

44

(65.7%)

67

(74.4%)

0.23

Major adverse cardiac events

17

(25.4%)

35

(38.9%)

0.08

Abnormal ABI

32

(47.8%)

72

(80.0%)

<0.01*

Renal function

    

0.09

 Normal renal function

(eGFR ≥60)

31

(46.3%)

27

(30.0%)

 

 Chronic kidney disease

(eGFR <60)

23

(34.3%)

36

(40.0%)

 

 Dialysis

13

(19.4%)

27

(30.0%)

 

HbA1c (%)

9.7

(±2.5)

9.0

(±2.9)

0.14

Hospitalization duration (days)

48.2

(±34.7)

36.9

(±25.2)

0.03*

  1. *Significance: P value <0.05
  2. +Including continuous variables of age and diabetes duration; and categorical variables of gender, smoking status, hypertension, major adverse cardiac events, ankle-brachial index, and renal function
  3. LEA lower-extremity amputation, ABI ankle-brachial index, eGFR estimated glomerular filtration rate