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Table 1 Demographics and clinical characteristics of the patients with diabetes and infectious foot gangrene and risk factors for mortality in a Cox proportional hazards model (Total number: 157)

From: Survival and associated risk factors in patients with diabetes and amputations caused by infectious foot gangrene

Characteristic

Mean (standard deviation) or Number (%)

Multivariate+ analysis

Mortality HR (95% CI)

P value

Age (years)

66.8

(±10.8)

1.04*(1.01–1.06)

0.01

Gender

   

0.37

 Female

58

(36.9%)

1

 

 Male

99

(63.1%)

0.79 (0.46–1.33)

 

Diabetes duration (years)

12.8

(±8.4)

1.14 (0.92–1.43)

0.24

Smoking status

34

(21.7%)

1.48 (0.73–3.01)

0.28

Hypertension

111

(70.7%)

1.06 (0.63–1.80)

0.83

Major adverse cardiac events

52

(33.1%)

1.48 (0.88–2.50)

0.14

Abnormal ABI

104

(66.2%)

1.28 (0.67–2.42)

0.46

Renal function

 Normal renal function

(eGFR ≥60)

58

(36.9%)

1

 

 Chronic kidney disease

(eGFR <60)

59

(37.6%)

0.87 (0.48–1.59)

0.66

 Dialysis

40

(25.5%)

2.09^(0.99–4.41)

0.05

HbA1c (%)

9.4

(±2.7)

1.02 (0.92–1.13)

0.71

Limb amputation status

 Minor LEA

67

(42.7%)

1

 

 Major LEA

90

(57.3%)

1.80*(1.05–3.09)

0.03

  1. *Significance: P value <0.05
  2. ^Borderline significance: P value = 0.05
  3. +Including continuous variables of age, diabetes duration, and HbA1c; and categorical variables of gender, smoking status, hypertension, major adverse cardiac events, ankle-brachial index, renal function and LEA status
  4. HR hazard ratio, ABI ankle-brachial index, eGFR estimated glomerular filtration rate, LEA lower-extremity amputation
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Journal of Foot and Ankle Research

ISSN: 1757-1146