Characteristic
|
Mean (standard deviation) or Number (%)
|
Multivariate+ analysis
|
---|
Mortality HR (95% CI)
|
P value
|
---|
Age (years)
|
66.8
|
(±10.8)
|
1.04*(1.01–1.06)
|
0.01
|
Gender
| | | |
0.37
|
Female
|
58
|
(36.9%)
|
1
| |
Male
|
99
|
(63.1%)
|
0.79 (0.46–1.33)
| |
Diabetes duration (years)
|
12.8
|
(±8.4)
|
1.14 (0.92–1.43)
|
0.24
|
Smoking status
|
34
|
(21.7%)
|
1.48 (0.73–3.01)
|
0.28
|
Hypertension
|
111
|
(70.7%)
|
1.06 (0.63–1.80)
|
0.83
|
Major adverse cardiac events
|
52
|
(33.1%)
|
1.48 (0.88–2.50)
|
0.14
|
Abnormal ABI
|
104
|
(66.2%)
|
1.28 (0.67–2.42)
|
0.46
|
Renal function
|
Normal renal function
(eGFR ≥60)
|
58
|
(36.9%)
|
1
| |
Chronic kidney disease
(eGFR <60)
|
59
|
(37.6%)
|
0.87 (0.48–1.59)
|
0.66
|
Dialysis
|
40
|
(25.5%)
|
2.09^(0.99–4.41)
|
0.05
|
HbA1c (%)
|
9.4
|
(±2.7)
|
1.02 (0.92–1.13)
|
0.71
|
Limb amputation status
|
Minor LEA
|
67
|
(42.7%)
|
1
| |
Major LEA
|
90
|
(57.3%)
|
1.80*(1.05–3.09)
|
0.03
|
- *Significance: P value <0.05
- ^Borderline significance: P value = 0.05
- +Including continuous variables of age, diabetes duration, and HbA1c; and categorical variables of gender, smoking status, hypertension, major adverse cardiac events, ankle-brachial index, renal function and LEA status
- HR hazard ratio, ABI ankle-brachial index, eGFR estimated glomerular filtration rate, LEA lower-extremity amputation