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Table 3 Association between tophus location at each site in the foot and ankle and muscle forcea

From: Clinically-evident tophi are associated with reduced muscle force in the foot and ankle in people with gout: a cross-sectional study

  

Least-squares mean (SD)

Diff.

95% CI

P

Tophus location

Absent

Present

Lower

Upper

Plantarflexion force

Hallux

91.3 (30.2)

72.1 (29.4)

19.1

−2.6

40.9

0.083

Lesser Toes

92.2 (30.1)

77.5 (29.4)

14.7

−0.9

30.3

0.065

First MTP

91.0 (30.4)

77.7 (29.8)

13.4

−6.1

32.8

0.175

Lesser MTPs

89.6 (30.5)

100.0 (29.3)

−10.3

−52.3

31.6

0.627

Midfoot

89.4 (30.4)

101.6 (29.8)

−12.3

−42.4

17.9

0.422

Heel

89.3 (30.3)

117.5 (28.6)

−28.2

−69.6

13.2

0.177

Achilles

94.2 (29.1)

65.1 (29.3)

29.1

13.2

45.0

<0.001

Dorsiflexion force

Hallux

68.1 (26.8)

47.9 (25.8)

20.2

1.1

39.3

0.038

Lesser Toes

67.9 (27.3)

59.5 (26.8)

8.4

−5.8

22.6

0.243

First MTP

66.5 (27.5)

67.3 (27.0)

−0.7

−18.4

16.9

0.933

Lesser MTPs

66.9 (27.4)

52.3 (26.3)

14.6

−23.1

52.3

0.444

Midfoot

66.0 (27.3)

81.4 (26.8)

−15.4

−42.6

11.7

0.262

Heel

66.1 (27.2)

94.8 (27.2)

−28.7

−68.0

10.6

0.149

Achilles

69.4 (27.1)

51.2 (27.1)

18.2

3.4

32.9

0.016

Inversion force

Hallux

53.4 (19.1)

46.4 (18.8)

7.1

−6.8

21.0

0.314

Lesser Toes

53.7 (19.1)

48.7 (18.4)

5.0

−4.8

14.9

0.311

First MTP

53.0 (19.2)

52.2 (18.8)

0.8

−11.5

13.1

0.899

Lesser MTPs

53.0 (19.1)

48.6 (18.3)

4.4

−21.9

30.6

0.742

Midfoot

52.3 (18.9)

66.4 (18.4)

−14.1

−32.7

4.6

0.137

Heel

52.4 (18.8)

72.4 (16.8)

−20.0

−44.4

4.4

0.106

Achilles

54.9 (18.6)

40.9 (18.8)

14.0

3.8

24.2

0.008

Eversion force

Hallux

51.5 (18.2)

43.7 (17.4)

7.8

−5.1

20.8

0.233

Lesser Toes

50.9 (18.3)

50.9 (18.0)

0.0

−9.5

9.6

0.997

First MTP

50.9 (18.3)

50.6 (18.0)

0.3

−11.4

12.0

0.962

Lesser MTPs

50.9 (18.3)

48.9 (17.6)

2.0

−23.2

27.2

0.875

Midfoot

50.6 (18.2)

58.7 (17.9)

−8.2

−26.3

10.0

0.374

Heel

50.7 (18.2)

63.2 (18.6)

−12.5

−39.5

14.4

0.355

Achilles

53.4 (17.7)

37.0 (17.6)

16.4

6.8

26.0

0.001

  1. aResults are presented adjusted for gout disease duration, age and foot pain VAS. Bolded P values indicate significant difference between groups at Bonferroni-adjusted significance level of P < 0.0125. Diff. Difference in least-squares mean between the two groups, CI confidence interval