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Table 1 Participant characteristics

From: Clinically-evident tophi are associated with reduced muscle force in the foot and ankle in people with gout: a cross-sectional study

 

Foot or ankle tophi

P

Absent

Present

N

35

22

 

Male, n (%)

31 (89%)

19 (86%)

0.81

Age, years

60 (14)

60 (12)

0.89

BMI, kg/m2

33 (8)

33 (6)

0.68

Ethnicity

 European, n (%)

11 (31%)

6 (27%)

0.26

 Māori, n (%)

8 (23%)

3 (14%)

 Pacific, n (%)

13 (37%)

13 (59%)

 Asian, n (%)

3 (9%)

0 (0%)

Type 2 diabetes, n (%)

14 (40%)

7 (32%)

0.53

Stage 3 or worse chronic kidney disease, n (%)a

19 (54%)

17 (77%)

0.06

Hypertension, n (%)

26 (74%)

16 (73%)

0.90

Cardiovascular disease, n (%)

12 (34%)

6 (27%)

0.58

Gout disease duration, years

11 (10)

25 (13)

< 0.001

Gout flares in previous 3 months

0.6 (1.1)

0.5 (0.9)

0.55

Serum urate, mmol/L

0.41 (0.13)

0.39 (0.13)

0.58

Urate lowering therapy, n (%)

31 (89%)

21 (96%)

0.59

Total foot tophus count

0 (0)

4.6 (5.6)

0.001

Total body tophus count

1.7 (4.6)

12.9 (12.8)

0.001

Foot pain VAS, mm

5.7 (30.4)

15.5 (38.5)

0.05

Global pain VAS, mm

12.4 (27.9)

14.4 (35.5)

0.74

Manchester Foot Pain and Disability Index

10.6 (12.5)

16.6 (15.8)

0.044

  1. Values are mean (SD) unless otherwise specified. aDefined as estimated glomerular filtration rate (eGFR) of <60 mL/min/1.73mm2; bFor those in employment; Bolded P values indicate significant difference between groups at P < 0.05. BMI body mass index, VAS visual analogue scale