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Table 1 Comparison of PAD Characteristics [1, 23, 76,77,78,79]

From: The comparative efficacy of angiosome-directed and indirect revascularisation strategies to aid healing of chronic foot wounds in patients with co-morbid diabetes mellitus and critical limb ischaemia: a literature review

 

Patients with Diabetes

Patients without Diabetes

Age of onset

Younger

Older

Disease progression

Aggressive

Gradual

Anatomical localisation

• Mainly distal

• Distinctly infrapopliteal affliction, frequently involving all three tibial region arteries: Anterior Tibial, Posterior Tibial and Peroneal artery

• Relative sparing of inframalleolar pedal arteries (e.g. Dorsalis Pedis) and supragenicular arteries (e.g. Femoral and Aortic-iliac arteries).

• Mainly proximal

• Lesions tend to affect the Femoral and Aortic-iliac arteries more frequently than the distal arteries

Type of atherosclerotic lesions

• Stenosis < Occlusions (severe)

• Diffuse, and occurring over long segments

• Stenosis > Occlusions

• Focal, and occurring over short segments

Calcification

Commonly present

Absent

Collateral network

Poor

Unaffected