Variable | Control | Gout | Asymptomatic hyperuricaemia |
---|---|---|---|
N | 34 | 23 | 29 |
Gender, male, n (%) | 34 (100) | 23 (100) | 29 (100) |
Age, years | 58 (14) | 58 (14) | 58 (19) |
Ethnicity, n (%) | European 30 (88) | European 14 (61) | European 24 (83) |
Maori 1 (3) | Maori 1 (4) | Maori 0 (0) | |
Pacific 0 (0) | Pacific 4 (17) | Pacific 3 (10) | |
Asian 3 (9) | Asian 4 (17) | Asian 2 (7) | |
BMI, kg/m2 | 25.0 (2.9) | 30.8 (3.8)a | 29.3 (5.9)a |
Diuretic use, n (%) | 4 (12) | 3 (13) | 7 (24) |
NSAID use, n (%) | 7 (21) | 14 (61)a | 11 (38) |
Prednisone use, n (%) | 0 (0) | 5 (22) | 0 (0) |
Hypertension, n (%) | 9 (26) | 16 (70)a | 16 (55)a |
Cardiovascular disease, n (%) | 1 (3) | 6 (26)a | 5 (17) |
Diabetes, n (%) | 2 (6) | 4 (17) | 1 (3) |
Serum urate, mg/dl | 5.4 (1.0) | 5.9 (1.7) | 7.7 (0.8)a |
Disease duration, years | - | 18 (11) | - |
Number of acute flares in preceding 3Â months | - | 1.4 (1.4) | - |
1MTP flares in preceding 3Â months, n (%) | - | 6 (26) | - |
History of 1st MTP joint flares, n (%) | - | 19 (83) | - |
Presence of clinically-evident tophi at any site, n (%) | - | 17 (74) | - |
Presence of clinically-evident tophi at the 1st MTP joint, n (%)b | - | 6 (13) | - |
Urate lowering therapyb, n (%) | - | 22 (96) | - |
Microscopically-proven gout, n (%) | - | 6 (26) | - |
US double contour signb, n (%) | 9 (13) | 17 (37) | 21 (36) |
US tophusb, n (%) | 0 (0) | 6 (13) | 0 (0) |
US erosionb, n (%) | 2 (3) | 15 (33) | 1 (2) |
US synovitisb, n (%) | 5 (7) | 20 (44) | 2 (3) |
1st MTP joint pain VASb, mm | 1.6 (4.0) | 8.5 (15.6) | 6.9 (15.1) |
Manchester Foot Pain and Disability Index | 1.8 (6.0) | 13.4 (10.8) | 3.4 (4.8) |
1st MTP joint range of motionb, ° | 77.6 (17.4) | 59.0 (19.6) | 76.5 (16.9) |
1st MTP joint temperatureb, °C | 25.3 (2.1) | 27.4 (2.8) | 26.1 (2.2) |
Gait velocity, m/s | 1.05 (0.19) | 0.88 (0.17) | 1.05 (0.24) |