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Table 2 Intra-class correlation coefficients (ICC), 95% confidence intervals (CI), means Bland-Altman (B-A) limits of agreement and standard error of measurement (SEM) for cortical and trabecular densitometry of 12 ft bones (n = 10)

From: Computed tomography derived bone density measurement in the diabetic foot

  ICC 95% CI Mean (HU) Session 1 Mean (HU) Session 2 B-A Lower Limit B-A Upper Limit SEM
Trabecular
 Talus 0.91c 0.67, 0.98 457.88 491.11 −43.46 109.92 10.17
 Calcaneus 0.90c 0.64, 0.97 231.85 246.37 −50.59 79.63 9.1
 Navicular 0.70b 0.17, 0.92 367.88 386.1 −123.27 159.70 34.25
 Cuboid 0.68b 0.47, 0.91 227.12 223.4 −99.76 92.32 24.01
 Medial cuneiform 0.83c 0.46, 0.96 371.71 378.28 −125.75 138.89 24.12
 Intermediate cuneiform 0.88c 0.58, 0.97 498.84 493.5 −130.90 120.22 19.23
 Lateral cuneiform 0.86c 0.54, 0.96 373.96 355.08 −123.68 85.92 17.34
 First metatarsal 0.90c 0.66, 0.98 248.28 237.65 −82.08 60.83 9.99
 Second metatarsal 0.81c 0.40, 0.95 309.19 317.91 −137.69 155.14 28.21
 Third metatarsal 0.82c 0.44, 0.95 280.1 281.72 −100.64 103.87 19.18
 Fourth metatarsal 0.69b 0.15, 0.91 268.5 271.72 −128.62 135.06 32.45
 Fifth metatarsal 0.85c 0.50, 0.96 252.35 275.59 −74.44 120.93 16.72
Cortical
 Talus 0.52b −0.12, 0.85 2987.09 3111.51 −762.81 1011.66 271.73
 Calcaneus 0.59b −0.21, 0.88 2764.06 2693.04 −775.28 633.26 199.35
 Navicular 0.70b 0.18, 0.92 2823.12 2779.88 −578.67 492.18 129.64
 Cuboid 0.69b 0.16, 0.91 2573.46 2862.21 −380.13 957.64 161.96
 Medial cuneiform 0.17 −0.48, 0.70 2728.22 2672.93 −1006.28 895.71 382.99
 Intermediate cuneiform 0.46b −0.20, 0.83 2699.67 2735.92 −554.57 627.08 191.93
 Lateral cuneiform −0.18a −0.71, 0.47 2668.16 2717.88 −1007.55 1106.99 507.69
 First metatarsal 0.61b 0.01, 0.89 2897.07 2929.04 −633.15 697.11 183.62
 Second metatarsal −0.17a −0.70, 0.48 2872.36 2894.9 −960.78 1005.87 470.19
 Third metatarsal 0.22 −0.44, 0.72 2719.87 2892.68 −674.17 1019.79 330.67
 Fourth metatarsal −0.03a −0.62, 0.58 2728.13 2791.24 −974.57 1100.79 525.02
 Fifth metatarsal 0.37 −0.30, 0.80 2704.72 2716.83 −763.82 788.04 272.25
  1. HU Hounsfield units
  2. a the ICC obtained was negative due to greater intra-group variation than between group variation in that bone
  3. The measurement is unreliable bfair to good reliability, cexcellent reliability