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Table 6 Impact of different hypothetical protocols (D-Study) for QUS measurements recorded in transverse view

From: Quantitative ultrasound imaging of Achilles tendon integrity in symptomatic and asymptomatic individuals: reliability and minimal detectable change

QUS measurements in transverse view E = 1
V = 1 V = 2
I = 1 I = 2 I = 3 I = 1 I = 2 I = 3
Geometric
 Area (CSA) SYMPT Φ 0.96 0.97 0.98 0.98 0.99 0.99
SEM 0.07 0.05 0.05 0.05 0.04 0.03
MDC90%NORM 20.91 16.58 14.85 15.18 11.97 10.69
ASYMPT Φ 0.91 0.94 0.96 0.94 0.97 0.98
SEM 0.05 0.03 0.03 0.03 0.03 0.02
MDC90%NORM 18.96 14.50 12.67 14.38 10.89 9.45
 Thickness SYMPT Φ 0.96 0.97 0.97 0.98 0.98 0.99
SEM 0.04 0.04 0.03 0.03 0.03 0.03
MDC90%NORM 14.79 12.85 12.13 11.02 9.41 8.81
ASYMPT Φ 0.83 0.90 0.92 0.89 0.94 0.95
SEM 0.04 0.03 0.03 0.03 0.02 0.02
MDC90%NORM 17.46 13.18 11.41 13.72 10.24 8.78
 Width SYMPT Φ 0.82 0.89 0.92 0.90 0.94 0.96
SEM 0.09 0.06 0.06 0.06 0.05 0.04
MDC90%NORM 14.69 10.98 9.42 10.44 7.80 6.69
ASYMPT Φ 0.80 0.86 0.88 0.88 0.92 0.93
SEM 0.06 0.05 0.05 0.05 0.04 0.04
MDC90%NORM 11.61 9.55 8.75 8.56 6.97 6.35
Grayscale histogram
 Echogenicity SYMPT Φ 0.85 0.89 0.90 0.91 0.94 0.95
SEM 6.11 5.16 4.81 4.55 3.79 3.50
MDC90%NORM 16.47 13.91 12.95 12.25 10.20 9.42
ASYMPT Φ 0.81 0.88 0.91 0.90 0.94 0.95
SEM 5.25 3.94 3.39 3.71 2.79 2.40
MDC90%NORM 13.23 9.93 8.56 9.35 7.02 6.05
 Variance SYMPT Φ 0.47 0.53 0.55 0.61 0.68 0.70
SEM 179.83 159.58 152.23 134.27 116.89 110.49
MDC90%NORM 53.14 47.16 44.99 39.68 34.54 32.65
ASYMPT Φ 0.63 0.71 0.75 0.76 0.82 0.85
SEM 112.00 92.43 84.91 82.42 67.32 61.47
MDC90%NORM 34.41 28.40 26.09 25.32 20.68 18.89
 Skewness SYMPT Φ 0.47 0.60 0.66 0.64 0.75 0.80
SEM 0.19 0.15 0.13 0.13 0.10 0.09
MDC90%NORM 69.88 53.98 47.51 49.41 38.17 33.59
ASYMPT Φ 0.60 0.70 0.75 0.72 0.81 0.84
SEM 0.15 0.12 0.11 0.12 0.09 0.08
MDC90%NORM 69.85 55.19 49.35 53.67 41.75 36.94
 Kurtosis SYMPT Φ 0.38 0.48 0.52 0.52 0.63 0.67
  SEM 0.83 0.68 0.62 0.62 0.50 0.45
MDC90%NORM 51.01 41.66 38.04 38.09 30.71 27.81
ASYMPT Φ 0.45 0.57 0.63 0.56 0.68 0.74
SEM 0.58 0.45 0.40 0.47 0.36 0.31
MDC90%NORM 38.08 29.68 26.29 30.68 23.42 20.44
 Entropy SYMPT Φ 0.27 0.32 0.34 0.40 0.47 0.50
SEM 0.15 0.13 0.13 0.11 0.10 0.09
MDC90%NORM 5.17 4.58 4.37 3.82 3.34 3.16
ASYMPT Φ 0.63 0.73 0.77 0.75 0.83 0.86
SEM 0.09 0.07 0.06 0.07 0.05 0.05
MDC90%NORM 3.02 2.42 2.18 2.30 1.81 1.62
Co-occurrence matrix
 Contrast SYMPT Φ 0.81 0.85 0.87 0.88 0.92 0.93
SEM 0.08 0.07 0.06 0.06 0.05 0.04
MDC90%NORM 21.25 18.16 17.01 15.64 13.20 12.29
ASYMPT Φ 0.65 0.75 0.79 0.77 0.85 0.88
SEM 0.09 0.07 0.06 0.07 0.05 0.05
MDC90%NORM 22.63 17.82 15.90 16.89 13.17 11.67
 Energy SYMPT Φ 0.62 0.67 0.69 0.75 0.79 0.81
SEM 0.02 0.02 0.02 0.02 0.02 0.02
MDC90%NORM 39.31 35.16 33.67 28.93 25.50 24.25
ASYMPT Φ 0.78 0.85 0.87 0.87 0.91 0.93
SEM 0.02 0.01 0.01 0.01 0.01 0.01
MDC90%NORM 27.37 21.80 19.60 19.72 15.65 14.03
 Homogeneity SYMPT Φ 0.86 0.90 0.92 0.92 0.95 0.96
SEM 0.01 0.01 0.01 0.01 0.01 0.01
MDC90%NORM 3.61 2.92 2.65 2.55 2.07 1.87
ASYMPT Φ 0.76 0.85 0.89 0.85 0.92 0.94
SEM 0.01 0.01 0.01 0.01 0.01 0.01
MDC90%NORM 3.82 2.80 2.36 2.80 2.04 1.72