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Table 5 Impact of different hypothetical protocols (D-Study) for QUS measurements recorded in longitudinal view

From: Quantitative ultrasound imaging of Achilles tendon integrity in symptomatic and asymptomatic individuals: reliability and minimal detectable change

QUS measurements in longitudinal view E = 1
V = 1 V = 2
I = 1 I = 2 I = 3 I = 1 I = 2 I = 3
Geometric
 Thickness SYMPT Φ 0.85 0.88 0.90 0.90 0.93 0.94
SEM 0.09 0.07 0.07 0.07 0.06 0.05
MDC90%NORM 29.21 25.17 23.66 23.28 19.35 17.84
ASYMPT Φ 0.90 0.93 0.94 0.94 0.96 0.97
SEM 0.03 0.03 0.02 0.02 0.02 0.02
MDC90%NORM 14.52 11.80 10.74 10.94 8.76 7.90
Grayscale histogram
 Echogenicity SYMPT Φ 0.83 0.87 0.88 0.90 0.93 0.93
  SEM 6.35 5.56 5.27 4.65 4.03 3.79
MDC90%NORM 18.68 16.36 15.51 13.69 11.84 11.16
ASYMPT Φ 0.89 0.91 0.92 0.94 0.96 0.96
SEM 4.76 4.05 3.78 3.37 2.87 2.68
MDC90%NORM 13.31 11.32 10.57 9.43 8.01 7.48
 Variance SYMPT Φ 0.69 0.76 0.79 0.81 0.86 0.88
  SEM 157.27 131.36 121.51 111.20 92.89 85.92
MDC90%NORM 56.03 46.80 43.29 39.62 33.09 30.61
ASYMPT Φ 0.63 0.73 0.77 0.77 0.84 0.87
SEM 118.97 93.45 83.22 84.12 66.08 58.85
MDC90%NORM 45.85 36.01 32.07 32.42 25.47 22.68
 Skewness SYMPT Φ 0.42 0.59 0.69 0.58 0.74 0.81
SEM 0.29 0.21 0.17 0.21 0.15 0.12
MDC90%NORM 104.67 74.18 60.70 75.60 53.58 43.84
ASYMPT Φ 0.43 0.57 0.64 0.55 0.69 0.75
SEM 0.24 0.18 0.15 0.18 0.14 0.12
MDC90%NORM 116.65 87.95 76.02 90.96 67.84 58.13
 Kurtosis SYMPT Φ 0.30 0.42 0.49 0.46 0.59 0.66
SEM 1.50 1.15 1.00 1.06 0.81 0.71
MDC90%NORM 83.94 64.13 55.99 59.44 45.40 39.63
ASYMPT Φ 0.38 0.51 0.58 0.50 0.63 0.70
SEM 0.81 0.62 0.54 0.64 0.48 0.42
MDC90%NORM 51.31 39.27 34.34 40.69 30.67 26.51
 Entropy SYMPT Φ 0.70 0.75 0.77 0.82 0.85 0.87
SEM 0.17 0.15 0.14 0.12 0.10 0.10
MDC90%NORM 5.92 5.21 4.95 4.30 3.75 3.55
ASYMPT Φ 0.65 0.74 0.77 0.78 0.85 0.87
SEM 0.13 0.11 0.10 0.09 0.08 0.07
MDC90%NORM 4.79 3.85 3.48 3.39 2.72 2.46
Co-occurrence matrix
 Contrast SYMPT Φ 0.63 0.72 0.75 0.74 0.82 0.84
SEM 0.08 0.07 0.06 0.06 0.05 0.05
MDC90%NORM 30.57 25.20 23.14 23.72 19.11 17.30
ASYMPT Φ 0.66 0.76 0.80 0.79 0.87 0.89
SEM 0.08 0.06 0.05 0.06 0.04 0.04
MDC90%NORM 28.23 21.88 19.30 19.96 15.47 13.65
 Energy SYMPT Φ 0.60 0.68 0.71 0.75 0.80 0.83
SEM 0.03 0.03 0.02 0.02 0.02 0.02
MDC90%NORM 33.74 28.73 26.85 24.39 20.63 19.21
ASYMPT Φ 0.64 0.74 0.78 0.78 0.85 0.88
SEM 0.03 0.02 0.02 0.02 0.02 0.02
MDC90%NORM 34.26 27.17 24.35 24.22 19.21 17.22
 Homogeneity SYMPT Φ 0.63 0.71 0.75 0.75 0.82 0.85
SEM 0.02 0.01 0.01 0.01 0.01 0.01
MDC90%NORM 4.72 3.85 3.52 3.54 2.85 2.58
ASYMPT Φ 0.71 0.80 0.83 0.83 0.89 0.91
SEM 0.01 0.01 0.01 0.01 0.01 0.01
MDC90%NORM 4.45 3.50 3.12 3.15 2.48 2.21