Charcot arthropathy inclusion (n = 28) | Charcot arthropathy end of study (n = 27) | Diabetic controls inclusion (n = 20) | Diabetic controls +2Y (n = 20) | Healthy subjects (n = 20) | |
---|---|---|---|---|---|
Age (median- range, years) | 61 (42–87) | 63 (42–87) | 55 (20–94) | 57 (20–94) | 58 (24–78) |
Gender (n) | |||||
Females | 1012 | 101011 | 8 | 8 | 9 |
Males | 16 | 16 | 12 | 12 | 11 |
Diabetes type 1/2 (n) | 11/1517 | 11/1516 | 6/14 | 6/14 | - |
Diabetes duration (years) | 25 ± 4 | - | 14 ± 6 | - | - |
Debut foot symptoms (weeks, median-range) | 8.4 (1–24) | - | - | - | - |
Systolic blood pressure (mmHg) | 149 ± 6 | 148 ± 6 | 127 ± 4 | - | 138 ± 4 |
Diastolic blood pressure (mmHg) | 80 ± 3 | 80 ± 3 | 76 ± 2 | - | 81 ± 3 |
Arterial toe pressure (mmHg) | |||||
Charcot foot | 114112 ± 11 | 122 ± 8 | 115 ± 4 | - | - |
Contralateral foot | 129128 ± 8 | 119 ± 7 | 114 ± 5 | - | - |
Skin temperature (°C) | |||||
Charcot foot | 31.331.6 ± 0.8a | 29.7 ± 0.7 | 30,0 ± 0,4 | - | - |
Contralateral foot | 28.8 ± 0.9 | 29.3 ± 0.7 | 30,2 ± 0,4 | - | - |
Pain at rest (n) | 4 | 0 | 0 | - | - |
Pain at weight bearing (n) | 17 | 0 | 0 | - | - |
Foot distorsion (n) | 4 | 4 | 0 | - | 0 |
Total contact cast (months) | - | 7.7 ± 1.0 | - | - | - |
Charcot pattern I/II/III/IV/V (n) | 2/16/57/0/3 | - | - | - | - |
Nephropathy/Cardiac disease (n) | 7/4 | 7/4 | 2/1 | 2/1 | 0/0 |
Hb (g/L) | 127 ± 3 | 129 ± 3 | 136 ± 2 | 139 ± 3 | 143 ± 5 |
S-CRP (mg/L) | 10.611.2 ± 3b,c | 10.09.8 ± 2d,e | 3.6 ± 0,8 | 3.8 ± 0,8 | 2.7 ± 0,7 |
SR (mm) | 28.831.1 ± 6f,g | 23 ± 5 | 11 ± 2 | 10 ± 2 | 6 ± 4 |
S-Kreatinin (μmol/L) | 112116 ± 19 | 101 ± 12 | 83 ± 8 | 89 ± 7 | 78 ± 5 |
HbA1c (mmol/mol) | 60 ± 3 | 64 ± 2 | 58 ± 3 | 56 ± 2 | - |
HbA1c (%) | 7.8 ± 0.3 | 7.4 ± 0.3 | 7.5 ± 0.2 | 7.3 ± 0.2 | - |