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Table 4 Factors associated with foot pain in the last month

From: Foot problems in people with gout in primary care: baseline findings from a prospective cohort study

 

Foot pain in last month n (%)

No foot pain in last month n (%)

Unadjusted OR (95 % CI)

Adjusteda OR (95 % CI)

N

248

875

-

-

Age, mean (SD)

66.6 (11.7)

65.0 (12.7)

1.11b (0.99, 1.24)

1.14b (0.94, 1.38)

Gender:

    

 Male

190 (76.6)

752 (85.9)

1.0

1.0

 Female

58 (23.4)

123 (14.1)

1.87 (1.31, 2.65)

1.33 (0.77, 2.30)

Neighbourhood deprivation tertiles:

    

 Most deprived

93 (37.5)

258 (29.5)

1.0

1.0

 Mid-deprived

78 (31.5)

304 (34.7)

0.71 (0.50, 1.00)

0.81 (0.50, 1.31)

 Least deprived

77 (31.1)

313 (35.8)

0.68 (0.48, 0.96)

1.14 (0.71, 1.82)

BMI (kg/m2):

    

 <25.0

34 (15.2)

177 (21.1)

1.0

1.0

 25.0–29.9

90 (40.2)

397 (47.2)

1.18 (0.77, 1.82)

1.64 (0.89, 2.99)

 30.0–34.9

62 (27.7)

182 (21.6)

1.77 (1.11, 2.83)

2.23 (1.16, 4.27)

 ≥35.0

38 (17.0)

85 (10.1)

2.33 (1.37, 3.95)

2.61 (1.25, 5.45)

Anxiety:

    

 None

133 (60.7)

677 (81.8)

1.0

1.0

 Mild

41 (18.7)

96 (11.6)

2.17 (1.44, 3.28)

1.05 (0.57, 1.95)

 Moderate

25 (11.4)

34 (4.1)

3.74 (2.16, 6.48)

1.38 (0.56, 3.39)

 Severe

20 (9.1)

21 (2.5)

4.85 (2.56, 9.19)

1.21 (0.41, 3.51)

Depression:

    

 None

93 (47.0)

644 (80.2)

1.0

1.0

 Mild

52 (26.3)

90 (11.2)

4.00 (2.67, 6.00)

3.02 (1.78, 5.11)

 Moderate

20 (10.1)

43 (5.4)

3.22 (1.82, 5.71)

1.42 (0.58, 3.46)

 Moderately severe

20 (10.1)

18 (2.2)

7.69 (3.93, 15.08)

3.41 (1.22, 9.57)

 Severe

13 (6.6)

8 (1.0)

11.25 (4.54, 27.88)

4.55 (1.20, 17.18)

Comorbidity:

    

 Diabetes mellitus

59 (23.8)

134 (15.3)

1.73 (1.22, 2.44)

1.00 (0.60, 1.66)

 Hypertension

166 (66.9)

529 (60.5)

1.32 (0.98, 1.78)

0.98 (0.62, 1.57)

 Hyperlipidaemia

117 (47.2)

374 (42.7)

1.20 (0.90, 1.59)

1.12 (0.74, 1.71)

 Ischaemic heart disease

56 (22.6)

140 (16.0)

1.53 (1.08, 2.17)

1.43 (0.87, 2.35)

 Cerebrovascular disease

18 (7.3)

62 (7.1)

1.03 (0.60, 1.77)

0.83 (0.40, 1.69)

Gout characteristics:

    

 Duration, mean (SD)

12.7 (13.4)

11.8 (11.8)

1.06c (0.94, 1.20)

1.05c (0.88, 1.25)

 Current attack

62 (26.1)

65 (7.7)

4.21 (2.87, 6.19)

2.38 (1.35, 4.20)

 Number of attacks in last 12 months:

    

  0

63 (27.2)

313 (37.5)

1.0

1.0

  1–2

77 (33.2)

323 (38.7)

1.18 (0.82, 1.71)

0.96 (0.58, 1.59)

  ≥3

92 (39.7)

199 (23.8)

2.30 (1.59, 3.31)

1.17 (0.66, 2.05)

 Oligo/polyarticular attacks

132 (56.4)

289 (34.4)

2.47 (1.84, 3.32)

1.67 (1.11, 2.51)

 Current allopurinol use

144 (62.1)

463 (55.6)

1.31 (0.97, 1.76)

1.11 (0.72, 1.72)

  1. BMI body mass index, CI confidence interval, OR odds ratio, SD standard deviation
  2. aOR adjusted for age, gender, deprivation, BMI, anxiety, depression, comorbidity and gout characteristics
  3. bper 10-year increase in age
  4. cper 10-year increase in duration of disease