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Table 1 Selected scaliness parameters, hydration, elasticity, collagen & elastin fibre organisation and fissure depth measures testing intra – rater reliability

From: The reliability of non-invasive biophysical outcome measures for evaluating normal and hyperkeratotic foot skin

     

Bland - Altman data

  

ICC agreement

95 % CI

SEM consistency

Mean difference [SD]

95 % LOA

Investigator A

      

Callus

Hydration [AU]

0.61

−0.95 - 0.93

0.26

−1.25 [3.11]

−7.30 – 4.80

 

Elasticity [mm]

0.77

−0.17 - 0.97

0.06

0.30 [0.40]

−0.47 – 1.08

 

Collagen and elastin fibre organisation [AU]

0.98

0.88 - 1.00

6.76

1.69 [44.50]

−85.50 – 88.92

 

SEsm [AU]

0.88

0.34 – 0.98

1.23

−0.61 [24.76]

−49.13 – 47.91

 

SEr [AU]

0.84

0.10 – 0.97

0.29

−0.10 [1.74]

−3.51 – 3.31

 

SEsc [AU]

0.38

0.84 – 1.51

0.03

−0.20 [0.38]

−0.94 – 0.55

Heel fissure

Hydration [AU]

0.93

0.26 – 0.99

0.35

0.26 [2.33]

−4.30 – 4.82

 

Elasticity [mm]

0.82

−4.42 – 1.00

0.00

0.03 [0.10]

−0.16 – 0.21

 

SEsm [AU]

1.00

8.85 – 0.90

0.00

−11.35 [33.12]

−76.27 – 53.57

 

SEr [AU]

0.38

0.97 – 6.14

1.24

−0.20 [2.47]

−5.03 – 4.63

 

SEsc [AU]

0.73

0.98 – 21.89

0.04

−0.07 [0.12]

−0.29 – 0.16

 

Fissure depth [μm]

0.95

0.46 – 1.00

4.83

−20.08 [29.74]

−78.37 – 38.21

Xerotic plantar heel skin

Hydration [AU]

0.88

−0.49 – 1.00

0.37

0.59 [2.05]

−3.43 – 4.61

 

Elasticity [mm]

0.53

−9.25 – 0.97

0.01

−0.05 [0.11]

−0.25 – 0.16

 

Collagen and elastin fibre organisation [AU]

0.98

0.33 – 1.00

0.51

−12.58 [8.37]

−28.98 – 3.83

 

SEsm [AU]

0.51

0.46 – 0.96

14.13

−27.07 [20.70]

−67.64 – 13.51

 

SEr [AU]

0.68

0.82 – 2.17

0.17

−0.71 [0.84]

−2.35 – 0.94

 

SEsc [AU]

0.31

0.93 – 7.56

0.41

0.33 [0.59]

−0.82 – 1.47

PMA

Hydration [AU]

0.97

0.86 – 1.00

0.16

−0.35 [2.64]

−5.50 – 4.82

 

Elasticity [mm]

0.45

−2.68 – 0.92

7.9 x10−5

0.08 [0.19]

−0.31 – 0.46

 

Collagen and elastin fibre organisation [AU]

0.88

0.32 – 0.98

32.02

18.06 [95.33]

−168.80 – 204.90

 

SEsm [AU]

0.96

0.84 – 0.99

0.07

−0.61 [10.65]

−21.48 – 20.26

 

SEr [AU]

0.76

0.06 – 0.94

0.48

−0.24 [2.06]

−4.28 – 3.79

 

SEsc [AU]

0.78

0.14 – 0.94

0.08

−0.07 [0.64]

−1.32 – 1.18

5th met. base

Hydration [AU]

0.92

0.73 – 0.98

0.15

−1.10 [2.77]

−6.51 – 4.32

 

Elasticity [mm]

0.80

0.11 – 0.95

0.34

−0.02 [0.16]

−0.33 – 0.30

 

Collagen and elastin fibre organisation [AU]

0.98

0.92 – 1.00

4.16

1.61 [36.50]

−69.92 – 73.14

 

SEsm [AU]

0.72

0.24 – 0.90

0.44

−4.18 [22.91]

−49.09 – 40.73

 

SEr [AU]

0.66

0.03 – 0.88

0.31

0.11 [1.16]

−2.17 – 2.38

 

SEsc [AU]

0.72

0.23 – 0.90

0.49

0.17 [1.21]

−2.20 – 2.53

     

Bland – Altman data

  

ICC agreement

95 % CI

SEM consistency

Mean difference [SD]

95 % LOA

Investigator B

      

Callus

Hydration [AU]

0.40

−3.17 – 0.90

0.73

−0.99 [3.67]

−8.18 – 6.19

 

Elasticity [mm]

0.98

0.82 – 1.00

0.02

0.01 [0.17]

−0.34 – 0.35

 

Collagen and elastin fibre organisation [AU]

1.00

0.92 – 1.00

5.62

18.87 [46.12]

−71.54 – 109.30

 

SEsm [AU]

0.82

0.11 – 0.96

0.34

4.97 [22.52]

−39.17 – 49.11

 

SEr [AU]

0.84

0.19 – 0.97

0.43

0.40 [1.99]

−3.50 – 4.30

 

SEsc [AU]

0.89

 

0.02

−0.15 [0.24]

−0.61 – 0.31

Heel fissure

Hydration [AU]

0.89

−0.28 – 1.00

0.94

0.29 [3.21]

−6.01 – 6.60

 

Elasticity [mm]

0.95

−0.05 – 1.00

0.00

−0.06 [0.02]

−0.10 – 0.01

 

SEsm [AU]

0.68

0.94 – 5.03

12.62

4.97 [22.52]

−39.17 – 49.11

 

SEr [AU]

0.67

0.98 – 32.45

1.21

0.44 [2.29]

−4.05 – 4.94

 

SEsc [AU]

0.61

0.98 – 20.97

0.02

0.06 [0.17]

−0.28 – 0.39

 

Fissure depth [μm]

0.64

0.47 – 0.93

49.90

5.56 [14.06]

−270.10 – 281.20

Xerotic plantar heel skin

Hydration [AU]

0.84

−0.52 – 0.98

0.64

0.68 [2.40]

−4.03 – 5.38

 

Elasticity [mm]

0.40

7.74 – 0.96

0.01

−0.18 [0.07]

−0.15 – 0.12

 

Collagen and elastin fibre organisation [AU]

0.86

−0.19 – 0.99

6.55

−16.98 [19.34]

−54.88 – 20.93

 

SEsm [AU]

0.76

0.71 – 0.98

8.04

−15.60 [21.64]

−58.01 – 26.82

 

SEr [AU]

0.37

0.66 – 0.94

0.05

−0.64 [0.58]

−1.77 – 0.49

 

SEsc [AU]

0.86

0.22 – 0.99

0.06

0.11 [0.19]

−0.26 – 0.48

PMA

Hydration [AU]

1.00

0.89 – 1.00

0.00

−1.43 [1.92]

−5.20 – 2.33

 

Elasticity [mm]

0.55

−6.05 – 0.94

0.04

0.00 [0.15]

−3.00 – 0.30

 

Collagen and elastin fibre organisation [AU]

0.96

0.75 – 0.99

5.42

−5.96 [37.55]

−79.56 – 67.64

 

SEsm [AU]

0.95

0.81 – 0.99

1.46

5.33 [11.50]

−17.21 – 27.87

 

SEr [AU]

0.89

0.58 – 0.97

0.09

−0.05 [1.04]

−2.10 – 1.98

 

SEsc [AU]

0.89

0.59 – 0.97

0.28

−0.21 [0.42]

−1.02 – 0.61

5th met. base

Hydration [AU]

0.91

0.72 – 0.98

0.16

−1.20 [3.90]

−8.85 – 6.45

 

Elasticity [mm]

0.54

−0.45 – 0.88

0.03

0.05 [0.10]

−0.14 – 0.25

 

Collagen and elastin fibre organisation [AU]

0.99

0.95 – 1.00

3.17

−65.61 [88.91]

−65.61 – 88.91

 

SEsm [AU]

0.92

0.78 – 0.97

2.93

−4.16 [11.29]

−26.30 – 17.97

 

SEr [AU]

0.84

0.52 – 0.94

0.12

0.51 [0.90]

−1.26 – 2.28

 

SEsc [AU]

0.88

0.67 – 0.96

0.07

0.03 [0.48]

−0.91 – 0.96