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Table 3 Patient demographics and wound characteristics

From: Cost-effectiveness of clostridial collagenase ointment on wound closure in patients with diabetic foot ulcers: economic analysis of results from a multicenter, randomized, open-label trial

  Total CCO Control p-value
Demographic (n = 55) (n = 28) (n = 27) ANOVA/Chi-square
Age     
Mean ± SD 57.9 ± 12.3 56.9 ± 12.0 59.0 ± 12.7 0.54
Minimum, Maximum 35.0, 97.0 35.0, 97.0 39.0, 88.0  
Geriatric, n (%)     
<85 years 52 (94.5) 27 (96.4) 25 (92.6) 0.53
≥85 years 3 (5.5) 1 (3.6) 2 (7.4)  
Sex, n (%)     
Men 41 (74.5) 21 (75.0) 20 (74.1) 0.94
Women 14 (25.5) 7 (25.0) 7 (25.9)  
Race, n (%)     
White/Caucasian 47 (85.5) 25 (89.3) 22 (81.5) 0.41
Black/African American 8 (14.5) 3 (10.7) 5 (18.5)  
Ethnicity, n (%)     
Hispanic/Latino 9 (16.4) 5 (17.9) 4 (14.8) 0.76
Non-Hispanic/Latino 46 (83.6) 23 (82.1) 23 (85.2)  
Ankle brachial index, n (%)     
n* 33 (60.0%) 16 (57.1) 17 (63.0) 0.52
Mean ± SD 1.0 ± 0.1 1.0 ± 0.1 1.0 ± 0.1  
Minimum, Maximum 0.8, 1.1 0.8, 1.1 0.8, 1.1  
Wound area (cm 2 )     
Mean ± SD 1.9 ± 1.4 2.0 ± 1.1 1.8 ± 1.6 0.73
Minimum, Maximum 0.1, 7.5 0.1, 4.6 0.2, 7.5  
Wound location, n (%)     
Distal 2 (3.6) 1 (3.6) 1 (3.7) 0.38
Lateral 3 (5.5) 2 (7.1) 1 (3.7)  
Lateral/dorsal/distal 1 (1.8) 0 (0.0) 1 (3.7)  
Plantar 43 (78.2) 20 (71.4) 23 (85.2)  
Plantar/medial 6 (10.9) 5 (17.9) 1 (3.7)  
Wound side, n (%)     
Left foot 31 (56.4) 14 (50.0) 17 (63.0) 0.33
Right foot 24 (43.6) 14 (50.0) 10 (37.0)  
Number of sharp debridements     
6 Treatment weeks     
Mean ± SD 4.05 ± 1.83 4.07 ± 1.88 4.04 ± 1.81 0.45
Minimum, Maximum 1.0, 6.0 1.0, 6.0 1.0, 6.0  
6 Follow-up treatments     
N 39 (70.9%) 20 (71.4%) 19 (70.4%)  
Mean ± SD 3.11 ± 2.32 3.32 ± 2.24 2.89 ± 2.45 0.81
Minimum, Maximum 0.0, 6.0 0.0, 6.0 0.0, 6.0  
  1. ANOVA, analysis of variance; CCO, clostridial collagenase ointment; SD, standard deviation.
  2. *Not all patients had an ankle brachial index assessment.