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Table 3 Patient demographics and wound characteristics

From: Cost-effectiveness of clostridial collagenase ointment on wound closure in patients with diabetic foot ulcers: economic analysis of results from a multicenter, randomized, open-label trial

 

Total

CCO

Control

p-value

Demographic

(n = 55)

(n = 28)

(n = 27)

ANOVA/Chi-square

Age

    

Mean ± SD

57.9 ± 12.3

56.9 ± 12.0

59.0 ± 12.7

0.54

Minimum, Maximum

35.0, 97.0

35.0, 97.0

39.0, 88.0

 

Geriatric, n (%)

    

<85 years

52 (94.5)

27 (96.4)

25 (92.6)

0.53

≥85 years

3 (5.5)

1 (3.6)

2 (7.4)

 

Sex, n (%)

    

Men

41 (74.5)

21 (75.0)

20 (74.1)

0.94

Women

14 (25.5)

7 (25.0)

7 (25.9)

 

Race, n (%)

    

White/Caucasian

47 (85.5)

25 (89.3)

22 (81.5)

0.41

Black/African American

8 (14.5)

3 (10.7)

5 (18.5)

 

Ethnicity, n (%)

    

Hispanic/Latino

9 (16.4)

5 (17.9)

4 (14.8)

0.76

Non-Hispanic/Latino

46 (83.6)

23 (82.1)

23 (85.2)

 

Ankle brachial index, n (%)

    

n*

33 (60.0%)

16 (57.1)

17 (63.0)

0.52

Mean ± SD

1.0 ± 0.1

1.0 ± 0.1

1.0 ± 0.1

 

Minimum, Maximum

0.8, 1.1

0.8, 1.1

0.8, 1.1

 

Wound area (cm 2 )

    

Mean ± SD

1.9 ± 1.4

2.0 ± 1.1

1.8 ± 1.6

0.73

Minimum, Maximum

0.1, 7.5

0.1, 4.6

0.2, 7.5

 

Wound location, n (%)

    

Distal

2 (3.6)

1 (3.6)

1 (3.7)

0.38

Lateral

3 (5.5)

2 (7.1)

1 (3.7)

 

Lateral/dorsal/distal

1 (1.8)

0 (0.0)

1 (3.7)

 

Plantar

43 (78.2)

20 (71.4)

23 (85.2)

 

Plantar/medial

6 (10.9)

5 (17.9)

1 (3.7)

 

Wound side, n (%)

    

Left foot

31 (56.4)

14 (50.0)

17 (63.0)

0.33

Right foot

24 (43.6)

14 (50.0)

10 (37.0)

 

Number of sharp debridements

    

6 Treatment weeks

    

Mean ± SD

4.05 ± 1.83

4.07 ± 1.88

4.04 ± 1.81

0.45

Minimum, Maximum

1.0, 6.0

1.0, 6.0

1.0, 6.0

 

6 Follow-up treatments

    

N

39 (70.9%)

20 (71.4%)

19 (70.4%)

 

Mean ± SD

3.11 ± 2.32

3.32 ± 2.24

2.89 ± 2.45

0.81

Minimum, Maximum

0.0, 6.0

0.0, 6.0

0.0, 6.0

 
  1. ANOVA, analysis of variance; CCO, clostridial collagenase ointment; SD, standard deviation.
  2. *Not all patients had an ankle brachial index assessment.