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Table 1 Percent of occurrence and transition probabilities

From: Cost-effectiveness of clostridial collagenase ointment on wound closure in patients with diabetic foot ulcers: economic analysis of results from a multicenter, randomized, open-label trial

Parameter Percent Weekly transition probability
CCO + SSD healing rate*   
Weeks 1, 6, 9, and 11 5.0 0.05
Weeks 2, 4, and 12 10.0 0.10
Weeks 3, 5, 7, 10, and 19-52 0.0 0.00
Week 8 15.0 0.15
Weeks 13-18 6.9 0.07
Control healing rate*   
Weeks 1-2, 4, 6-7, 9, 11, and 26-52 0.0 0.00
Week 3 15.0 0.15
Weeks 5 and 10 5.0 0.05
Weeks 8 and 12 11.0 0.11
Weeks 13-25 5.6 0.06
Ulcer recurrence   
Weeks 1-52 47.1 0.01
All-cause mortality 0.0147 <0.01
  1. CCO, clostridial collagenase ointment; SSD, serial sharp debridement.
  2. *NCT01408277, Briggs et al. [31-33].
  3. Persson et al. [34].
  4. Centers for Disease Control for 2010 for persons 35–95 years [30].