Cost-effectiveness of steroid (methylprednisolone) injections versus anaesthetic alone for the treatment of Morton’s neuroma: economic evaluation alongside a randomised controlled trial (MortISE trial)

Table 3 Foot health thermometer scores and EQ-5D-3L utility index at baseline, 1 and 3 months

Outcome measure^a	(Control n = 55, Steroid n = 54)
	Mean (SD)		Mean adjusted for the baseline (SE)		Estimated difference^b[95% CI] significance
	Control	Steroid	Control	Steroid	Estimated difference^b[95% CI] significance
EQ-5D-3L utility index
Baseline	0.5831 (0.2947)	0.5346 (0.3023)	Not applicable	Not applicable	Not applicable
1 month	0.6213 (0.2523)	0.6129 (0.2717)	0.6178 (0.0351)	0.6164 (0.0354)	−0.0014 (−0.0976, 0.1004) p = 0.98
3 months	0.5944 (0.2852)	0.6226 (0.2771)	0.5930 (0.0388)	0.6241 (0.0388)	0.0311 (−0.0780, 0.1403) p = 0.57
QALY	0.1510 (0.0522)	0.1506 (0.0511)	0.1473 (0.0062)	0.1511 (0.0068)	0.0038 (−0.0146, 0.0221) p = 0.68
Foot health thermometer scores
Baseline	48.17 (23.68)	45.23 (21.22)	Not applicable	Not applicable	Not applicable
1 month	49.30 (24.21)	60.28 (22.01)	48.49 (3.07)	60.81 (3.10)	12.32 (3.66, 20.98) p = 0.006
3 months	53.06 (26.77)	64.26 (22.05)	52.77 (3.36)	64.69 (3.32)	11.92 (2.54, 21.29) p = 0.013
FHT-AUC	12.469 (5.061)	14.738 (4.038)	12.276 (0.504)	14.748 (0.556)	2.472 (0.986, 3.958) p = 0.001

^aImputed where necessary.
^bIn the final column, positive differences represent a better outcome for participants in the steroid group, and results in bold type are significant at 5% level.

ISSN: 1757-1146